2014
Characterization of a lanthanide complex encapsulated with MRI contrast agents into liposomes for biosensor imaging of redundant deviation in shifts (BIRDS)
Maritim S, Huang Y, Coman D, Hyder F. Characterization of a lanthanide complex encapsulated with MRI contrast agents into liposomes for biosensor imaging of redundant deviation in shifts (BIRDS). JBIC Journal Of Biological Inorganic Chemistry 2014, 19: 1385-1398. PMID: 25304046, PMCID: PMC4348029, DOI: 10.1007/s00775-014-1200-z.Peer-Reviewed Original ResearchConceptsLanthanide complexesMagnetic resonance imaging (MRI) probesParamagnetic lanthanide complexesT2 contrast agentsRedundant deviationMolecular imagingMRI contrast agentsNon-exchangeable protonsContrast agentsMRI contrastChemical shiftsMRI probesLiposomal encapsulation efficiencyParamagnetic environmentSignal amplificationEncapsulation efficiencyWater relaxationProbe environmentTransverse relaxation timeParamagnetic effectImaging probeHigh spatial resolutionParamagnetic agentsParamagnetic contrast agentRelaxation time
2012
Quantitative fMRI and oxidative neuroenergetics
Hyder F, Rothman DL. Quantitative fMRI and oxidative neuroenergetics. NeuroImage 2012, 62: 985-994. PMID: 22542993, PMCID: PMC3389300, DOI: 10.1016/j.neuroimage.2012.04.027.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingNeuronal activityQuantitative functional magnetic resonance imagingTotal neuronal activityBlood oxygenation level-dependent (BOLD) signalBrain energy metabolismResting-state paradigmLevel-dependent signalMagnetic resonance imagingSynaptic activityResonance imagingParamagnetic contrast agentFunctional brainBOLD contrastBaseline stateEnergy metabolismFunctional mapsContrast agentsMagnetic resonance spectroscopyFMRI dataRegion of interestActivityNeuroenergeticsBrain