2023
Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions
de Arce K, Ribic A, Chowdhury D, Watters K, Thompson G, Sanganahalli B, Lippard E, Rohlmann A, Strittmatter S, Missler M, Hyder F, Biederer T. Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions. Nature Communications 2023, 14: 459. PMID: 36709330, PMCID: PMC9884278, DOI: 10.1038/s41467-023-36042-w.Peer-Reviewed Original ResearchConceptsPrefrontal cortexDKO miceSynCAM 1Aberrant neuronal activityDendritic spine numberPrefrontal cortex synapsesSynapse organizersSynapse numberMature brainNeuronal activityKnockout miceSpine numberSynapse developmentCognitive functionTrans-synaptic complexesImmunoglobulin family membersMiceFamily membersSynapsesLRRTM1Behavioral domainsHippocampusCognitive tasksConcerted roleCortex
1997
“Willed action”: A functional MRI study of the human prefrontal cortex during a sensorimotor task
Hyder F, Phelps E, Wiggins C, Labar K, Blamire A, Shulman R. “Willed action”: A functional MRI study of the human prefrontal cortex during a sensorimotor task. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 6989-6994. PMID: 9192679, PMCID: PMC21272, DOI: 10.1073/pnas.94.13.6989.Peer-Reviewed Original ResearchConceptsDorsolateral prefrontal cortexPrefrontal cortexVerbal fluency taskFunctional MRISensorimotor tasksPositron emission tomography studyLeft dorsolateral prefrontal cortexEmission tomography studiesFunctional MRI studyFluency taskWilled actionHuman prefrontal cortexHealthy subjectsPET resultsMRI studiesBilateral activationCoronal slicesPET studiesTomography studyCortexFMRI dataFMRI studyActivation fociBrain activityHuman brain activity