2013
Glutamatergic Function in the Resting Awake Human Brain is Supported by Uniformly High Oxidative Energy
Hyder F, Fulbright RK, Shulman RG, Rothman DL. Glutamatergic Function in the Resting Awake Human Brain is Supported by Uniformly High Oxidative Energy. Cerebrovascular And Brain Metabolism Reviews 2013, 33: 339-347. PMID: 23299240, PMCID: PMC3587823, DOI: 10.1038/jcbfm.2012.207.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingMagnetic resonance spectroscopy studyAwake resting stateFuture clinical investigationsMagnetic resonance imagingHigh resting activityAwake human brainGray matter regionsGlutamatergic functionGlutamatergic signalingMetabolic measuresClinical investigationAwake stateResting activityVisual cortexGlucose utilizationResonance imaging
2012
Analysis of Time and Space Invariance of BOLD Responses in the Rat Visual System
Bailey CJ, Sanganahalli BG, Herman P, Blumenfeld H, Gjedde A, Hyder F. Analysis of Time and Space Invariance of BOLD Responses in the Rat Visual System. Cerebral Cortex 2012, 23: 210-222. PMID: 22298731, PMCID: PMC3513959, DOI: 10.1093/cercor/bhs008.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingGeneral linear modelingSuperior colliculusBOLD responseBasal blood flowNeural activityRat visual systemBlood oxygenation level-dependent (BOLD) responsePrimary visual cortexMagnetic resonance imagingLevel-dependent responsesNeurovascular couplingRat brainBlood flowVisual cortexResonance imagingStimulation paradigmV1 signalsLight flashesOnset/Neural signalsResponseV1Visual systemColliculus
2001
Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures
Petroff O, Hyder F, Rothman D, Mattson R. Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures. Neurology 2001, 56: 709-715. PMID: 11274303, DOI: 10.1212/wnl.56.6.709.Peer-Reviewed Original ResearchConceptsComplex partial seizuresJuvenile myoclonic epilepsyGamma-aminobutyric acidHigher homocarnosine levelsGood seizure controlSeizure controlPoor seizure controlHomocarnosine levelsPartial seizuresMyoclonic epilepsyBrain gamma-aminobutyric acidLower GABA levelsType of epilepsyLower gamma-aminobutyric acidGABA levelsOccipital cortexPatientsVisual cortexEpilepsyValproateLamotrigineSeizuresCortexHomocarnosineMR spectrometer