2015
Impact of red blood cell alloimmunization on sickle cell disease mortality: a case series
Nickel RS, Hendrickson JE, Fasano RM, Meyer EK, Winkler AM, Yee MM, Lane PA, Jones YA, Pashankar FD, New T, Josephson CD, Stowell SR. Impact of red blood cell alloimmunization on sickle cell disease mortality: a case series. Transfusion 2015, 56: 107-114. PMID: 26509333, DOI: 10.1111/trf.13379.Peer-Reviewed Original ResearchConceptsHemolytic transfusion reactionsRBC alloimmunizationTransfusion supportAlloimmunized patientsSerious hemolytic transfusion reactionsSickle cell disease careRed blood cell transfusionRed blood cell alloimmunizationCompatible RBC unitsBlood cell transfusionRBC transfusion supportDirect clinical consequencesNonalloimmunized patientsCell transfusionClinical courseRBC transfusionWorse survivalCase seriesDisease careDisease mortalityImmunologic differencesTransfusion reactionsClinical impactClinical consequencesCompatible blood
2012
Massive splenic infarction in an adolescent with hemoglobin S‐HPFH
Whyte D, Forget B, Chui DH, Luo H, Pashankar F. Massive splenic infarction in an adolescent with hemoglobin S‐HPFH. Pediatric Blood & Cancer 2012, 60: e49-e51. PMID: 23281181, DOI: 10.1002/pbc.24444.Peer-Reviewed Original ResearchConceptsMassive splenic infarctVaso-occlusive crisisBenign clinical courseMassive splenic infarctionHistory of anemiaSickle cell anemiaClinical courseClinical suspicionSevere complicationsSplenic infarctSplenic infarctionHb S mutationCell anemiaAnemiaCompound heterozygosityFetal hemoglobinComplicationsPatientsS mutationsLittle evidenceHigh levelsInfarctionInfarctsHospitalSuspicion