2020
Characterization of Wnt signaling pathway (WSP) aberrations in advanced prostate cancer.
Ghali F, Patel D, Jamieson C, Parsons J, McKay R. Characterization of Wnt signaling pathway (WSP) aberrations in advanced prostate cancer. Journal Of Clinical Oncology 2020, 38: 203-203. DOI: 10.1200/jco.2020.38.6_suppl.203.Peer-Reviewed Original ResearchProstate cancerOverall survivalActivating mutationsDe novo metastatic diseaseAdvanced prostate cancerSomatic activating mutationsEligible patientsAdvanced diseaseGleason 8Visceral metastasesClinical characteristicsMetastatic diseaseOverall cohortMedian ageMedian timePCa patientsDisease characteristicsOutcome parametersCRPC developmentBiomarker statusDisease progressionMultiple malignanciesTreatment strategiesClinical significanceBRCA1/2 alterations
2019
Prostatectomy in men with clinically positive lymph nodes.
Ghali F, Ryan S, Hansen M, Hayn M, Sammon J, Sarkar R, Murphy J, Kader A, Rose B. Prostatectomy in men with clinically positive lymph nodes. Journal Of Clinical Oncology 2019, 37: 327-327. DOI: 10.1200/jco.2019.37.7_suppl.327.Peer-Reviewed Original ResearchCox proportional hazards modelPositive lymph nodesBiopsy Gleason scoreProportional hazards modelProstate cancerLymph nodesPCa patientsGleason scoreHazards modelClinical positive lymph nodesHigh-risk prostate cancerNational Cancer DatabaseRisk prostate cancerPrimary treatment modalityPositive surgical marginsPathologic T stageDifficult clinical scenariosMedian followWorse OSNodal statusRisk patientsSystemic therapyClinical stagingSurgical marginsT stage