Impact of positive surgical margins on survival after partial nephrectomy in localized kidney cancer: analysis of the National Cancer Database
Ryan S, Patel D, Ghali F, Patel S, Sarkar R, Yim K, Eldefrawy A, Cotta B, Bradshaw A, Meagher M, Hamilton Z, Murphy J, Derweesh I. Impact of positive surgical margins on survival after partial nephrectomy in localized kidney cancer: analysis of the National Cancer Database. Minerva Urologica E Nefrologica 2020, 73: 233-244. PMID: 32748614, DOI: 10.23736/s2724-6051.20.03728-5.Peer-Reviewed Original ResearchConceptsPositive surgical marginsKaplan-Meier analysisRenal cell carcinomaNational Cancer DatabaseOverall survivalPartial nephrectomyMultivariable analysisSurgical marginsPathological stageCancer DatabaseCox regression multivariable analysisN0M0 renal cell carcinomaUS National Cancer DatabaseImpact of PSMRegression multivariable analysisPT3a diseaseCause mortalityMargin statusNegative marginsResection strategyCell carcinomaAggressive surveillanceRetrospective analysisKidney cancerPatientsComparison of renal functional outcomes of active surveillance and partial nephrectomy in the management of oncocytoma
Meagher M, Lane B, Capitanio U, Mehrazin R, Bradshaw A, Noyes S, Larcher A, Eldefrawy A, Ghali F, Patel D, Bruinius J, Dutt R, Keiner C, Miller N, Wan F, Montorsi F, Derweesh I. Comparison of renal functional outcomes of active surveillance and partial nephrectomy in the management of oncocytoma. World Journal Of Urology 2020, 39: 1195-1201. PMID: 32556559, DOI: 10.1007/s00345-020-03299-5.Peer-Reviewed Original ResearchConceptsDe novo chronic kidney diseaseChronic kidney diseaseKaplan-Meier analysisPartial nephrectomyActive surveillanceMultivariable analysisBaseline eGFRTumor sizeFunctional outcomeFunctional declineCKD-free survivalGreater functional declineHigher RENAL scoreLower baseline eGFRRenal functional preservationRegression multivariable analysisClinical tumor sizeRenal functional outcomesTumor diameterKidney diseaseRENAL scoreFunctional preservationMedian changeRetrospective analysisSelect circumstancesAssociation of robotic partial nephrectomy for clinical T2a renal mass with improved trifecta outcome compared to open partial nephrectomy: A single surgeon comparative analysis.
Ghali F, Elbakry A, Hamilton Z, Nasseri R, Eldefrawy A, Ryan S, Yim K, Patel S, Bradshaw A, Meagher M, Reddy M, Lee H, Derweesh I. Association of robotic partial nephrectomy for clinical T2a renal mass with improved trifecta outcome compared to open partial nephrectomy: A single surgeon comparative analysis. Journal Of Clinical Oncology 2020, 38: 653-653. DOI: 10.1200/jco.2020.38.6_suppl.653.Peer-Reviewed Original ResearchRobotic partial nephrectomyOpen PNPartial nephrectomyMultivariable analysisRENAL scoreRenal massesLower blood lossFirst-line optionMedian RENAL scoreAchievement of trifectaEGFR recoveryHospital staySelect patientsBlood lossConsecutive patientsMajor complicationsPositive marginsTumor sizeFunctional outcomeTrifecta achievementTrifecta outcomesRetrospective analysisMAIN OUTCOMESurgical qualityTrifecta rates