2009
Zoledronate reduces unwanted bone resorption in intercalary bone allografts
Seo SW, Cho SK, Storer SK, Lee FY. Zoledronate reduces unwanted bone resorption in intercalary bone allografts. International Orthopaedics 2009, 34: 599-603. PMID: 19343345, PMCID: PMC2903128, DOI: 10.1007/s00264-009-0748-7.Peer-Reviewed Original ResearchConceptsAllograft resorptionIntercalary allograftsBone resorptionBone allograftControl groupZoledronate solutionIntercalary bone allograftsBone formationBone mineral densitySynthetic pyrophosphate analoguesHigh-dose bisphosphonatesPharmacological modificationGraft incorporationMineral densityBone densityAllograftsIdeal doseResorptionAnimal trialsHistological analysisBisphosphonatesSegmental defectsPyrophosphate analogsExperimental groupRat femur
2002
Repair of Bone Allograft Fracture Using Bone Morphogenetic Protein-2
Lee FY, Storer S, Hazan EJ, Gebhardt MC, Mankin HJ. Repair of Bone Allograft Fracture Using Bone Morphogenetic Protein-2. Clinical Orthopaedics And Related Research® 2002, 397: 119-126. PMID: 11953604, DOI: 10.1097/00003086-200204000-00017.Peer-Reviewed Original ResearchConceptsAllograft fractureNormal fracture healingFracture healingProtein 2Long-term clinical dataExtensive tumour surgeryBone morphogenetic protein-2Major revision surgeryMorphogenetic protein-2Experimental groupOnly fibrosisRadiographic unionNew bone formationRevision surgeryAdditional ratsClinical dataTumor surgeryBone allograftAllograft boneControl groupBiologic regulatorsOsteotomy siteFracture repairRecombinant human bone morphogenetic protein-2Adequate function