2017
Tendon stem/progenitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling
Tarafder S, Chen E, Jun Y, Kao K, Sim KH, Back J, Lee FY, Lee CH. Tendon stem/progenitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling. The FASEB Journal 2017, 31: 3991-3998. PMID: 28533328, PMCID: PMC5572690, DOI: 10.1096/fj.201700071r.Peer-Reviewed Original ResearchConceptsConnective tissue growth factorTendon stem/progenitor cellsIL-10 expressionStem/progenitor cellsIL-10TIMP-3 expressionTendon healingIL-1βProgenitor cellsTendon cellsElevated IL-10 expressionAnti-inflammatory IL-10Number of iNOSRat patellar tendonAnti-inflammatory roleAcute tendon injuryIL-6 expressionRegulation of inflammationTissue growth factorMMP-3 expressionNumber of CD146Improved tendon healingDifferent anatomic locationsWestern blot analysisPromising regenerative potential
2011
Interleukin‐1β stimulates stromal‐derived factor‐1α expression in human subacromial bursa
Blaine TA, Cote MA, Proto A, Mulcahey M, Lee FY, Bigliani LU. Interleukin‐1β stimulates stromal‐derived factor‐1α expression in human subacromial bursa. Journal Of Orthopaedic Research® 2011, 29: 1695-1699. PMID: 21484857, DOI: 10.1002/jor.21416.Peer-Reviewed Original ResearchConceptsHuman subacromial bursaIL-1βIL-6SDF-1α expressionRotator cuff diseaseSubacromial bursaSubacromial bursitisSDF-1α productionSDF-1αCuff diseaseSDF-1α mRNA expressionBursal cellsInterleukin IL-1βSubacromial bursal tissueDose-dependent increaseFactor-1α expressionAnti-human antibodiesSupernatants of cellsRheumatoid controlsLocal cytokinesInflammatory cellsShoulder surgeryInterleukin-1βInflammatory responseIL-1