2017
Paraneoplastic Syndromes and Thymic Malignancies: An Examination of the International Thymic Malignancy Interest Group Retrospective Database
Padda SK, Yao X, Antonicelli A, Riess JW, Shang Y, Shrager JB, Korst R, Detterbeck F, Huang J, Burt BM, Wakelee HA, Badve SS. Paraneoplastic Syndromes and Thymic Malignancies: An Examination of the International Thymic Malignancy Interest Group Retrospective Database. Journal Of Thoracic Oncology 2017, 13: 436-446. PMID: 29191778, PMCID: PMC5983900, DOI: 10.1016/j.jtho.2017.11.118.Peer-Reviewed Original ResearchConceptsThymic epithelial tumorsIndependent prognostic factorOverall survivalPrognostic factorsPrognostic roleRetrospective databaseCox proportional hazards modelKaplan-Meier methodRecurrence-free survivalProportional hazards modelParaneoplastic syndromeCumulative incidenceResection statusTotal thymectomyMyasthenia gravisThymic malignanciesHistologic typeSyndrome statusFemale sexTreatment characteristicsEpithelial tumorsHazards modelLower CIRSyndromeMultivariate analysisThe Significance of Upfront Knowledge of N2 Disease in Non‐small Cell Lung Cancer
Thomas DC, Arnold BN, Rosen JE, Salazar MC, Detterbeck FC, Blasberg JD, Boffa DJ, Kim AW. The Significance of Upfront Knowledge of N2 Disease in Non‐small Cell Lung Cancer. World Journal Of Surgery 2017, 42: 161-171. PMID: 28799084, DOI: 10.1007/s00268-017-4165-6.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerUnsuspected N2 diseaseIII-N2 non-small cell lung cancerN2 diseaseCell lung cancerSurgical resectionAdjuvant chemotherapyAdjuvant therapyOverall survivalPathologic stageLung cancerMultivariate analysisCurative-intent surgical resectionStage IIIA NSCLCHigher comorbidity scoreNational Cancer DatabaseIndependent risk factorKaplan-Meier analysisCN2 diseaseIIIA NSCLCComorbidity scoreCancer DatabaseRisk factorsRetrospective analysisRadiation therapy
2014
Learning Curve to Lymph Node Resection in Minimally Invasive Esophagectomy for Cancer
Dhamija A, Rosen JE, Dhamija A, Rothberg BE, Kim AW, Detterbeck FC, Boffa DJ. Learning Curve to Lymph Node Resection in Minimally Invasive Esophagectomy for Cancer. Innovations Technology And Techniques In Cardiothoracic And Vascular Surgery 2014, 9: 286-291. PMID: 25084251, DOI: 10.1097/imi.0000000000000082.Peer-Reviewed Original ResearchConceptsLymph node yieldComplete resectionInvasive esophagectomyNode yieldSurgeon experienceMinimally Invasive EsophagectomyLymph node resectionSingle-surgeon seriesHigh-grade dysplasiaNode resectionComplete lymphadenectomyLymph nodesRetrospective reviewSurgical marginsOncologic efficacyNegative marginsOncologic aspectsInstitutional databaseEsophageal cancerInvasive approachLate subgroupsOpen approachMultivariate analysisResectionSafe alternative
2011
Long-term survival after lung resection for non–small cell lung cancer with circulatory bypass: A systematic review
Muralidaran A, Detterbeck FC, Boffa DJ, Wang Z, Kim AW. Long-term survival after lung resection for non–small cell lung cancer with circulatory bypass: A systematic review. Journal Of Thoracic And Cardiovascular Surgery 2011, 142: 1137-1142. PMID: 21864854, DOI: 10.1016/j.jtcvs.2011.07.042.Peer-Reviewed Original ResearchConceptsNon-small cell lung cancerCell lung cancerLong-term survivalAdvanced non-small cell lung cancerCirculatory bypassLung cancerLung resectionMultivariate analysisSystematic reviewFavorable long-term survivalUnfavorable long-term survivalWorse long-term survivalCox proportional hazards modelUnplanned cardiopulmonary bypassPrimary end pointKaplan-Meier methodCox regression modelProportional hazards modelPerioperative mortalityExtended resectionCardiopulmonary bypassClinical variablesExclusion criteriaResectionHazards model
2006
Clinical Value of the WHO Classification System of Thymoma
Detterbeck FC. Clinical Value of the WHO Classification System of Thymoma. The Annals Of Thoracic Surgery 2006, 81: 2328-2334. PMID: 16731193, DOI: 10.1016/j.athoracsur.2005.11.067.Peer-Reviewed Original ResearchConceptsWHO systemWorld Health Organization histologic classification systemWHO classification systemIndependent prognostic valueDistinct patient groupsHistologic classification systemClinical management decisionsWHO typePrognostic valuePatient groupClinical valueMultivariate analysisClassification systemThymoma