2021
The 2021 WHO Classification of Tumors of the Thymus and Mediastinum: What Is New in Thymic Epithelial, Germ Cell, and Mesenchymal Tumors?
Marx A, Chan JKC, Chalabreysse L, Dacic S, Detterbeck F, French CA, Hornick JL, Inagaki H, Jain D, Lazar AJ, Marino M, Marom EM, Moreira AL, Nicholson AG, Noguchi M, Nonaka D, Papotti MG, Porubsky S, Sholl LM, Tateyama H, Thomas de Montpréville V, Travis WD, Rajan A, Roden AC, Ströbel P. The 2021 WHO Classification of Tumors of the Thymus and Mediastinum: What Is New in Thymic Epithelial, Germ Cell, and Mesenchymal Tumors? Journal Of Thoracic Oncology 2021, 17: 200-213. PMID: 34695605, DOI: 10.1016/j.jtho.2021.10.010.Peer-Reviewed Original ResearchConceptsThymic epithelial tumorsGerm cell tumorsCell tumorsMesenchymal neoplasmsWHO classificationEpithelial tumorsMediastinal germ cell tumorsLow tumor mutational burdenTumor mutational burdenNew tumor entityClear cell carcinomaPositron emission tomographyClassification of tumorsThymic EpithelialThymic carcinomaFifth editionB3 thymomaTargetable mutationsCell carcinomaMesenchymal tumorsMetaplastic thymomaImmunohistochemical characterizationClinical informationMutational burdenDiagnostic advances
2017
Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database
Korst RJ, Fernando S, Catlin AC, Rutledge JR, Girard N, Huang J, Detterbeck F, Database C. Positron Emission Tomography in Thymic Tumors: Analysis Using a Prospective Research Database. The Annals Of Thoracic Surgery 2017, 104: 1815-1820. PMID: 29033016, PMCID: PMC5785101, DOI: 10.1016/j.athoracsur.2017.06.053.Peer-Reviewed Original ResearchConceptsPositron emission tomographyInternational Thymic Malignancy Interest GroupHistologic typeThymic malignanciesPretreatment workupPathologic stageEmission tomographyProspective databaseThymic tumorsTumor stageMaximum standardized uptake valueProspective research databaseHistologic tumor typeThymic epithelial tumorsStandardized uptake valueCharacteristic curveAnalysis of receiverClinicopathologic featuresRare tumorEpithelial tumorsLarge cohortResearch DatabaseUptake valueTumor typesPatients
2010
Imaging Requirements in the Practice of Pulmonary Metastasectomy
Detterbeck FC, Grodzki T, Gleeson F, Robert JH. Imaging Requirements in the Practice of Pulmonary Metastasectomy. Journal Of Thoracic Oncology 2010, 5: s134-s139. PMID: 20502248, DOI: 10.1097/jto.0b013e3181dcf64d.Peer-Reviewed Original ResearchConceptsHelical CT scansPulmonary metastasectomyCT scanThin-section scanningBetter patient selectionPrimary imaging modalityPositron emission tomographyPulmonary metastasesFurther metastasesMetastatic sitesPatient selectionSurveillance imagingPeriod of observationEmission tomographyMetastasisImaging modalitiesMetastasectomyReconstruction thicknessPatientsTomographyScansOptimal intervalFollowPalpationWeeksA Systematic Review of Restaging After Induction Therapy for Stage IIIa Lung Cancer: Prediction of Pathologic Stage
de Cabanyes Candela S, Detterbeck FC. A Systematic Review of Restaging After Induction Therapy for Stage IIIa Lung Cancer: Prediction of Pathologic Stage. Journal Of Thoracic Oncology 2010, 5: 389-398. PMID: 20186025, DOI: 10.1097/jto.0b013e3181ce3e5e.Peer-Reviewed Original ResearchConceptsInduction therapyPositron emission tomographyLung cancerComputed tomographySystematic reviewStage IIIA lung cancerEmission tomographyIIIA lung cancerMediastinal node involvementRepeat mediastinoscopyNode involvementComplete responsePathologic findingsEsophageal ultrasoundPathologic stageNeedle aspirationExpert handsRestagingFalse negative rateMediastinoscopyTherapyFN rateTomographyPatientsSurgery
2007
Beliefs among Physicians in the Diagnostic and Therapeutic Approach to Non-small Cell Lung Cancer
Stinchcombe TE, Detterbeck FC, Lin L, Rivera MP, Socinski MA. Beliefs among Physicians in the Diagnostic and Therapeutic Approach to Non-small Cell Lung Cancer. Journal Of Thoracic Oncology 2007, 2: 819-826. PMID: 17805059, DOI: 10.1097/jto.0b013e31811f478a.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, Non-Small-Cell LungClinical CompetenceCombined Modality TherapyFemaleHumansLung NeoplasmsMaleNeoplasm StagingOutcome Assessment, Health CarePractice Guidelines as TopicQuality of LifeRetrospective StudiesSeverity of Illness IndexSurveys and QuestionnairesSurvival RateUnited StatesConceptsEvidence-based guidelinesStage IV diseaseSolitary pulmonary nodulesLung cancerPhysicians' beliefsPractice beliefsPulmonary nodulesNon-small cell lung cancerRole of chemotherapyStage III diseaseMediastinal lymph nodesPostoperative radiation therapyCell lung cancerTreatment of patientsMajority of physiciansQuality of lifePositron emission tomographyReminder e-mailsAdjuvant chemotherapyOperable patientsSurvival benefitChest PhysiciansLymph nodesPractice patternsRadiation therapy
2004
Seeking a Home for a PET, Part 3 Emerging Applications of Positron Emission Tomography Imaging in the Management of Patients With Lung Cancer
Detterbeck FC, Vansteenkiste JF, Morris DE, Dooms CA, Khandani AH, Socinski MA. Seeking a Home for a PET, Part 3 Emerging Applications of Positron Emission Tomography Imaging in the Management of Patients With Lung Cancer. CHEST Journal 2004, 126: 1656-1666. PMID: 15539740, DOI: 10.1378/chest.126.5.1656.Peer-Reviewed Original ResearchConceptsManagement of patientsLung cancerPET imagingCycles of chemotherapyCompletion of treatmentPossible lung cancerIntensity of uptakePositron emission tomography (PET) imagingEmission Tomography ImagingPositron emission tomographyFurther technologic improvementsInduction therapyPatient outcomesBiological aggressivenessPatientsEmission tomographyTechnologic improvementsTomography imagingStaging approachRadiotherapy treatment fieldCancerTreatment fieldImagingTreatmentPET imagesSeeking a Home for a PET, Part 1 Defining the Appropriate Place for Positron Emission Tomography Imaging in the Diagnosis of Pulmonary Nodules or Masses
Detterbeck FC, Falen S, Rivera MP, Halle JS, Socinski MA. Seeking a Home for a PET, Part 1 Defining the Appropriate Place for Positron Emission Tomography Imaging in the Diagnosis of Pulmonary Nodules or Masses. CHEST Journal 2004, 125: 2294-2299. PMID: 15189954, DOI: 10.1378/chest.125.6.2294.Peer-Reviewed Original ResearchConceptsPositron emission tomographyLung cancerPulmonary nodulesEmission tomographyTypical carcinoid tumorEvaluation of symptomsIntermediate riskCarcinoid tumorsPulmonary lesionsBronchioloalveolar carcinomaRisk factorsHigh riskRadiographic appearancePatientsPET imagingLesionsDiagnosisLittle roleCancerTomographyRiskNodulesCarcinomaSymptomsTumorsSeeking a Home for a PET, Part 2 Defining the Appropriate Place for Positron Emission Tomography Imaging in the Staging of Patients With Suspected Lung Cancer
Detterbeck FC, Falen S, Rivera MP, Halle JS, Socinski MA. Seeking a Home for a PET, Part 2 Defining the Appropriate Place for Positron Emission Tomography Imaging in the Staging of Patients With Suspected Lung Cancer. CHEST Journal 2004, 125: 2300-2308. PMID: 15189955, DOI: 10.1378/chest.125.6.2300.Peer-Reviewed Original ResearchConceptsPositron emission tomographyLung cancerPET imagingClinical evaluationPET uptakeClinical stage I lung cancerStage I lung cancerStage III lung cancerEmission tomographyI lung cancerStrong clinical signsPositive PET resultsStaging of patientsInvasive mediastinal stagingNegative clinical evaluationExtrathoracic stagingMetastatic diseaseMediastinal stagingPrimary lesionClinical signsPET resultsPatientsCancerStagingDefinite role