2017
Interobserver Variation among Pathologists and Refinement of Criteria in Distinguishing Separate Primary Tumors from Intrapulmonary Metastases in Lung
Nicholson AG, Torkko K, Viola P, Duhig E, Geisinger K, Borczuk AC, Hiroshima K, Tsao MS, Warth A, Lantuejoul S, Russell PA, Thunnissen E, Marchevsky A, Mino-Kenudson M, Beasley MB, Botling J, Dacic S, Yatabe Y, Noguchi M, Travis WD, Kerr K, Hirsch FR, Chirieac LR, Wistuba II, Moreira A, Chung JH, Chou TY, Bubendorf L, Chen G, Pelosi G, Poleri C, Detterbeck FC, Franklin WA. Interobserver Variation among Pathologists and Refinement of Criteria in Distinguishing Separate Primary Tumors from Intrapulmonary Metastases in Lung. Journal Of Thoracic Oncology 2017, 13: 205-217. PMID: 29127023, PMCID: PMC6276791, DOI: 10.1016/j.jtho.2017.10.019.Peer-Reviewed Original ResearchConceptsSecond primary lung cancerIntrapulmonary metastasesComprehensive histologic assessmentHistologic featuresHistologic patternLung pathologistsHistologic assessmentNuclear pleomorphismMitotic rateSeparate primary tumorsPrimary lung cancerMain histologic typesPredominant patternDistinctive histologic featuresMultiple tumor nodulesClear cell changeRefinement of criteriaLepidic growthHistologic subtypeHistologic typeVascular invasionPrimary tumorLung cancerTumor extentLung tumorsIndications for invasive mediastinal staging in patients with early non-small cell lung cancer staged with PET-CT
Gao SJ, Kim AW, Puchalski JT, Bramley K, Detterbeck FC, Boffa DJ, Decker RH. Indications for invasive mediastinal staging in patients with early non-small cell lung cancer staged with PET-CT. Lung Cancer 2017, 109: 36-41. PMID: 28577947, DOI: 10.1016/j.lungcan.2017.04.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCarcinoma, Non-Small-Cell LungClinical Decision-MakingDiagnostic ImagingFemaleHumansLung NeoplasmsMaleMediastinumMiddle AgedNeoplasm MetastasisNeoplasm StagingPatient SelectionPositron Emission Tomography Computed TomographyPractice Guidelines as TopicRetrospective StudiesConceptsOccult N2 diseaseOccult N2 metastasesGround-glass componentInvasive mediastinal stagingCurative-intent therapyT2 tumorsN2 metastasisPET-CTInvasive stagingN2 diseaseT1 tumorsNegative predictive valueMediastinal stagingEarly non-small cell lung cancerExact testPredictive valueSolid tumorsNon-small cell lung cancerClinical stage I NSCLCN2 lymph nodesNode-negative NSCLCOccult nodal involvementPure-solid tumorsStage I NSCLCT1-2N0 disease
2016
Detection of Occult Micrometastases in Patients With Clinical Stage I Non–Small-Cell Lung Cancer: A Prospective Analysis of Mature Results of CALGB 9761 (Alliance)
Martin LW, D'Cunha J, Wang X, Herzan D, Gu L, Abraham N, Demmy TL, Detterbeck FC, Groth SS, Harpole DH, Krasna MJ, Kernstine K, Kohman LJ, Patterson GA, Sugarbaker DJ, Vollmer RT, Maddaus MA, Kratzke RA. Detection of Occult Micrometastases in Patients With Clinical Stage I Non–Small-Cell Lung Cancer: A Prospective Analysis of Mature Results of CALGB 9761 (Alliance). Journal Of Clinical Oncology 2016, 34: 1484-1491. PMID: 26926677, PMCID: PMC4872306, DOI: 10.1200/jco.2015.63.4543.Peer-Reviewed Original ResearchConceptsN2 lymph nodesStage I NSCLCDisease-free survivalOccult micrometastasesLymph nodesCell lung cancerOverall survivalLung cancerStage IClinical stage I NSCLCPathologic stage I NSCLCComplete surgical stagingClinical stage IRT-PCRDecreased overall survivalNegative lymph nodesWorse survival rateSquamous cell carcinomaReal-time reverse transcriptase-polymerase chain reactionMulti-institutional trialReverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionWarrants further investigationSurgical stagingPrognostic significance
2014
The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the N and M Components for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors
Kondo K, Van Schil P, Detterbeck FC, Okumura M, Stratton K, Giroux D, Asamura H, Crowley J, Falkson C, Filosso PL, Giaccone G, Huang J, Kim J, Lucchi M, Marino M, Marom EM, Nicholson AG, Ruffini E, Committee††† O, Boards‡‡‡ M, Domain§§§ P. The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: Proposals for the N and M Components for the Forthcoming (8th) Edition of the TNM Classification of Malignant Tumors. Journal Of Thoracic Oncology 2014, 9: s81-s87. PMID: 25396316, DOI: 10.1097/jto.0000000000000291.Peer-Reviewed Original ResearchMeSH KeywordsHumansLymphatic MetastasisNeoplasm MetastasisNeoplasm StagingNeoplasms, Glandular and EpithelialPrognosisSurvival AnalysisThymus Neoplasms
2013
Methods for Staging Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Silvestri GA, Gonzalez AV, Jantz MA, Margolis ML, Gould MK, Tanoue LT, Harris LJ, Detterbeck FC. Methods for Staging Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e211s-e250s. PMID: 23649440, DOI: 10.1378/chest.12-2355.Peer-Reviewed Original ResearchConceptsLung cancerPET scanningNeedle techniqueCT scanningMediastinal metastasesMetastatic diseasePractice guidelinesAmerican CollegeChest Physicians Evidence-Based Clinical Practice GuidelinesTissue biopsiesChest Physicians Lung Cancer GuidelinesEvidence-based clinical practice guidelinesNon-small cell lung cancer diagnosisNon-small cell lung cancerMediastinal lymph node metastasisCell lung cancer diagnosisLung cancer guidelinesPET scan findingsLymph node metastasisCell lung cancerClinical practice guidelinesLymph node stationsUnsuspected metastatic diseaseEndobronchial ultrasound needle aspirationPET-CT scanningThe Stage Classification of Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Detterbeck FC, Postmus PE, Tanoue LT. The Stage Classification of Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e191s-e210s. PMID: 23649438, DOI: 10.1378/chest.12-2354.Peer-Reviewed Original ResearchConceptsChest Physicians Evidence-Based Clinical Practice GuidelinesEvidence-based clinical practice guidelinesClinical practice guidelinesLung cancer diagnosisLung cancerTNM descriptorsPractice guidelinesAmerican CollegeSeventh editionCancer diagnosisStage classification systemClassification systemStage classificationCancerDiagnosisSpecial Treatment Issues in Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Kozower BD, Larner JM, Detterbeck FC, Jones DR. Special Treatment Issues in Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e369s-e399s. PMID: 23649447, DOI: 10.1378/chest.12-2362.Peer-Reviewed Original ResearchConceptsSecond primary lung cancerChest wall involvementPrimary lung cancerLung cancerSurgical resectionPancoast tumorWall involvementAmerican CollegeChest Physicians Evidence-Based Clinical Practice GuidelinesMetachronous second primary lung cancerEvidence-based clinical practice guidelinesNon-small cell lung cancer diagnosisNon-small cell lung cancerLonger disease-free intervalCell lung cancer diagnosisIpsilateral different lobeMediastinal node involvementN2 nodal diseaseSpecial clinical casesThoracic Oncology NetworkAggressive surgical approachDisease-free intervalPrimary surgical resectionExperienced multidisciplinary teamLarge prospective studies
2010
Coping with the unexpected at surgery
Detterbeck FC, Terrien CM. Coping with the unexpected at surgery. Expert Review Of Respiratory Medicine 2010, 4: 115-122. PMID: 20387297, DOI: 10.1586/ers.09.59.Peer-Reviewed Original ResearchConceptsLung cancer surgeryMultidisciplinary tumor boardN2 node involvementPN2 diseaseNode involvementT4 tumorsExperienced centersSuch patientsCancer surgeryPreoperative assessmentTumor boardChest wallBetter outcomesIntraoperative surprisesSurgeryResectionMediastinalPatientsTumorsCareful planningDisease
2009
Anatomy, Biology and Concepts, Pertaining to Lung Cancer Stage Classification
Detterbeck FC, Tanoue LT, Boffa DJ. Anatomy, Biology and Concepts, Pertaining to Lung Cancer Stage Classification. Journal Of Thoracic Oncology 2009, 4: 437-443. PMID: 19333070, DOI: 10.1097/jto.0b013e31819852ed.Peer-Reviewed Original ResearchNew TNM classification for non-small-cell lung cancer
Tanoue LT, Detterbeck FC. New TNM classification for non-small-cell lung cancer. Expert Review Of Anticancer Therapy 2009, 9: 413-423. PMID: 19374596, DOI: 10.1586/era.09.11.Peer-Reviewed Original Research
2003
Diagnosis of Lung Cancer* The Guidelines
Rivera MP, Detterbeck F, Mehta AC. Diagnosis of Lung Cancer* The Guidelines. CHEST Journal 2003, 123: 129s-136s. PMID: 12527572, DOI: 10.1378/chest.123.1_suppl.129s.Peer-Reviewed Original ResearchConceptsLung cancerAbnormal chest radiograph findingsOverall clinical statusChest radiograph findingsPresence of metastasesUnnecessary invasive proceduresAvailable diagnostic proceduresMethods of diagnosisRadiograph findingsClinical presentationClinical statusPrimary tumorIndividual patientsInvasive proceduresSystemic effectsParticular patientCancerDiagnostic proceduresDiagnostic approachPatientsDiagnostic issuesDiagnosisTumorsCareful judgmentMetastasisThe Noninvasive Staging of Non-small Cell Lung Cancer* The Guidelines
Silvestri GA, Tanoue LT, Margolis ML, Barker J, Detterbeck F. The Noninvasive Staging of Non-small Cell Lung Cancer* The Guidelines. CHEST Journal 2003, 123: 147s-156s. PMID: 12527574, DOI: 10.1378/chest.123.1_suppl.147s.Peer-Reviewed Original ResearchConceptsChest CT scanningMetastatic diseaseLung cancerCT scanningPhysical examinationClinical evaluationCT scanPET scansWhole body positron emission tomography scanningNon-small cell lung cancerImaging studiesPositron emission tomography scanningAbnormal scan findingsAbdominal CT scanCell lung cancerMalignant lymph nodesPresence of malignancyNoninvasive imaging studiesClinical evaluation toolCurative surgeryScan findingsBone scanLymph nodesTreatment optionsThorough history