2022
Associations of Renalase With Blood Pressure and Hypertension in Chinese Adults
Wang Y, Chen C, Hu GL, Chu C, Zhang XY, Du MF, Zou T, Zhou Q, Liao YY, Ma Q, Wang KK, Sun Y, Wang D, Yan Y, Li Y, Jia H, Niu ZJ, Zhang X, Wang L, Man ZY, Gao WH, Li CH, Zhang J, Gao K, Li HX, Chang J, Desir GV, Lu WH, Mu JJ. Associations of Renalase With Blood Pressure and Hypertension in Chinese Adults. Frontiers In Cardiovascular Medicine 2022, 9: 800427. PMID: 35282385, PMCID: PMC8907541, DOI: 10.3389/fcvm.2022.800427.Peer-Reviewed Original ResearchSerum renalase levelsRisk of hypertensionRenalase levelsRenal biopsy specimensHypertension incidenceRenalase expressionStudy cohortBiopsy specimensMean arterial pressure changesLongitudinal BP changesNon-hypertensive patientsDevelopment of hypertensionArterial pressure changesBlood pressure regulationExpression of renalaseHuman renal biopsy specimensBP progressionHypertensive patientsHypertensive subjectsNormotensive subjectsBlood pressureDiastolic BPSystolic BPRenal expressionSerum renalase
2010
The Evidence-Based Use of Thiazide Diuretics in Hypertension and Nephrolithiasis
Reilly RF, Peixoto AJ, Desir GV. The Evidence-Based Use of Thiazide Diuretics in Hypertension and Nephrolithiasis. Clinical Journal Of The American Society Of Nephrology 2010, 5: 1893-1903. PMID: 20798254, DOI: 10.2215/cjn.04670510.Peer-Reviewed Original ResearchConceptsUse of indapamideUrinary calcium excretionThiazide-type diureticsRandomized clinical trialsTreatment of hypertensionEvidence-based useDose-response effectPaucity of dataInitial therapyCalcium excretionHypertensive patientsOlder patientsThiazide diureticsStone recurrencePatient groupClinical trialsDrug classesSafe optionHypertensionDiureticsAvailable evidenceNephrolithiasisHydrochlorothiazideChlorthalidoneSafe track record