2013
Renalase protects against cisplatin acute kidney injury in mice
Desir G, Wang L, Velazquez H, Moeckel G, Safirstein R. Renalase protects against cisplatin acute kidney injury in mice. The FASEB Journal 2013, 27: 910.7-910.7. DOI: 10.1096/fasebj.27.1_supplement.910.7.Peer-Reviewed Original ResearchCisplatin acute kidney injuryAcute kidney injuryRenalase expressionKidney injuryCisplatin-induced acute kidney injuryIschemic acute kidney injuryRenal injury scoreUseful therapeutic optionHK-2 cellsImportant clinical syndromeRenalase deficiencyTubular necrosisPro-survival signalsTherapeutic optionsClinical syndromeInjury scorePlasma creatinineKO miceEffective therapyRenalaseBCL2 expressionMarked reductionProtective actionCaspase-3Injury
2012
Human renalase: a review of its biology, function, and implications for hypertension
Desir GV, Wang L, Peixoto AJ. Human renalase: a review of its biology, function, and implications for hypertension. International Journal Of Cardiology Cardiovascular Risk And Prevention 2012, 6: 417-426. PMID: 23107895, DOI: 10.1016/j.jash.2012.09.002.Peer-Reviewed Original ResearchConceptsMechanism of actionBlood pressureIschemic acute kidney injuryEnd-stage renal diseaseAcute kidney injuryHeart transplant recipientsChronic kidney diseaseAmbulatory blood pressureGlomerular filtration rateTarget organ injuryNormal control subjectsEnzyme-linked immunosorbent assayCatecholamine-like substancesRenalase deficiencyRenalase levelsKidney injuryTransplant recipientsRenal dopamineAcute administrationChronic administrationRenal diseaseKidney diseaseControl subjectsFiltration ratePlasma levels