1999
LONG-TERM FOLLOW-UP OF PATIENTS WITH OSTEOCHONDRAL ALLOGRAFTS A Correlation Between Immunologic Responses and Clinical Outcome
Friedlaender G, Strong D, Tomford W, Mankin H. LONG-TERM FOLLOW-UP OF PATIENTS WITH OSTEOCHONDRAL ALLOGRAFTS A Correlation Between Immunologic Responses and Clinical Outcome. Orthopedic Clinics Of North America 1999, 30: 583-588. PMID: 10471763, DOI: 10.1016/s0030-5898(05)70111-5.Peer-Reviewed Original ResearchConceptsClinical outcomesImmunologic responseHistocompatibility antigensLong-term clinical outcomesLong-term resultsFrozen bone allograftsPresence of sensitizationFrozen osteochondral allograftsImmune responseBone allograftAnimal modelsSatisfactory outcomeOsteochondral allograftsReconstructive alternativeClass IIBiologic successAllograftsOutcomesAntigenResponsePatientsHumansSensitization
1992
Immune responses to osteochondral allografts: nature and significance.
Friedlaender G, Horowitz M. Immune responses to osteochondral allografts: nature and significance. Orthopedics 1992, 15: 1171-5. PMID: 1409127, DOI: 10.3928/0147-7447-19921001-08.Peer-Reviewed Original ResearchConceptsImmune responseOsteochondral allograftsSuppressor/cytotoxic phenotypeBiologic significanceNumerous animal modelsT cell activationCell surface antigensMajor histocompatibility complexClinical resultsCytotoxic phenotypeBone allograftAnimal modelsSurface antigenBone graftAllograftsBiologic outcomesHistocompatibility complexCellular elementsGraftAntigenResponseImmunogenicitySignificance
1983
Immune responses to osteochondral allografts. Current knowledge and future directions.
Friedlaender G. Immune responses to osteochondral allografts. Current knowledge and future directions. Clinical Orthopaedics And Related Research® 1983, 58-68. PMID: 6339143.Peer-Reviewed Original ResearchConceptsImmune responseReconstructive joint surgeryGraft recipientsAllograft immunogenicityAllograft successHistocompatibility antigensJoint surgeryAnimal modelsBone graftOsteochondral allograftsHuman recipientsBiomechanical factorsAllograftsImmunogenHeterogeneous cell typesPreliminary evidenceImmunogenicityRecipientsCell typesCurrent knowledgeMatter of speculationSkeletal tissuesTissuePotent sourceResponse