1997
The Nicolas Andry Award-1995 Fracture Healing; Radiation Induced Alterations
Pelker R, Friedlaender G. The Nicolas Andry Award-1995 Fracture Healing; Radiation Induced Alterations. Clinical Orthopaedics And Related Research® 1997, 341: 267-282. PMID: 9269183, DOI: 10.1097/00003086-199708000-00038.Peer-Reviewed Original ResearchConceptsIncidence of fracturesNonunion of fracturesDose fractionation schemesRadiation-Induced AlterationsNicolas Andry AwardSingle doseFractionation schemeClinical observationsAllogeneic boneFracture healingIrradiated boneControl groupFinal repairIncidenceInduced alterationsRat femur modelNonunionDegree of delayFracturesImmature levelBoneRepairEffects of radiationAnimalsRefracture
1991
The influence of ibuprofen on fracture repair: Biomechanical, biochemical, histologic, and histomorphometric parameters in rats
Huo M, Troiano N, Pelker R, Gundberg C, Friedlaender G. The influence of ibuprofen on fracture repair: Biomechanical, biochemical, histologic, and histomorphometric parameters in rats. Journal Of Orthopaedic Research® 1991, 9: 383-390. PMID: 2010842, DOI: 10.1002/jor.1100090310.Peer-Reviewed Original ResearchConceptsControl animalsHistomorphometric parametersFracture repairUnilateral femur fracturesMature Sprague-Dawley ratsSerum osteocalcin levelsCyclo-oxygenase inhibitorSprague-Dawley ratsBone formation rateInfluence of ibuprofenOral doseFemur fracturesOsteocalcin levelsClinical practiceBone volumeBone remodelingInhibitory effectSignificant alterationsFracture biomechanicsRatsAnimalsTail vertebraePresent studyIbuprofenRepair
1975
A laboratory model for the study of the immunobiology of osteosarcoma
Friedlaender G, Mitchell M. A laboratory model for the study of the immunobiology of osteosarcoma. Cancer 1975, 36: 1631-1639. PMID: 172215, DOI: 10.1002/1097-0142(197511)36:5<1631::aid-cncr2820360516>3.0.co;2-w.Peer-Reviewed Original ResearchConceptsCell-mediated immunityRegression of diseaseWistar-Lewis ratsMoloney sarcomasMoloney sarcoma virusProgressive diseaseClinical courseLung metastasesMicrocytotoxicity assayTreatment protocolImmune responseImmunologic similaritiesHuman osteosarcomaSerum factorsTumor cellsMarrow cavityOsteosarcomaTarget cellsRatsTumorsDiseaseSarcoma virusAnimalsWeeks of inoculationTissue culture