2016
Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease.
Russo GS, Rubio DR, Yacob A, Lindskog DM, Alomari AK, Friedlaender GE. Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease. Connecticut Medicine 2016, 80: 399-403. PMID: 29782126.Peer-Reviewed Case Reports and Technical NotesConceptsGiant cell tumorAnterior cruciate ligamentCell tumorsIncidental findingRoutine preoperative imagingPre-operative MRIInitial MRIPreoperative imagingSecond MRIMetaphyseal lesionsCruciate ligamentEnlarged massBenign neoplasmsRetrospective evaluationNatural historyTumorsYoung womenHistory diseaseMRIBoneLesionsPainPatientsNeoplasmsHistology
1997
The Nicolas Andry Award-1995 Fracture Healing; Radiation Induced Alterations
Pelker R, Friedlaender G. The Nicolas Andry Award-1995 Fracture Healing; Radiation Induced Alterations. Clinical Orthopaedics And Related Research® 1997, 341: 267-282. PMID: 9269183, DOI: 10.1097/00003086-199708000-00038.Peer-Reviewed Original ResearchConceptsIncidence of fracturesNonunion of fracturesDose fractionation schemesRadiation-Induced AlterationsNicolas Andry AwardSingle doseFractionation schemeClinical observationsAllogeneic boneFracture healingIrradiated boneControl groupFinal repairIncidenceInduced alterationsRat femur modelNonunionDegree of delayFracturesImmature levelBoneRepairEffects of radiationAnimalsRefracture
1993
Effects of prefracture irradiation on the biomechanical parameters of fracture healing
Widmann R, Pelker R, Friedlaender G, Panjabi M, Peschel R. Effects of prefracture irradiation on the biomechanical parameters of fracture healing. Journal Of Orthopaedic Research® 1993, 11: 422-428. PMID: 8326449, DOI: 10.1002/jor.1100110315.Peer-Reviewed Original Research
1991
Induction of specific T-cell responsiveness to allogeneic bone.
Horowitz M, Friedlaender G. Induction of specific T-cell responsiveness to allogeneic bone. Journal Of Bone And Joint Surgery 1991, 73: 1157-68. PMID: 1716256, DOI: 10.2106/00004623-199173080-00004.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, Differentiation, T-LymphocyteBone and BonesBone MarrowBone TransplantationCells, CulturedCytotoxicity Tests, ImmunologicEpitopesLymphocyte ActivationLymphocyte Culture Test, MixedMajor Histocompatibility ComplexMiceMice, Inbred StrainsT-LymphocytesTransplantation, HomologousTransplantation, IsogeneicConceptsT cellsAllogeneic boneMajor histocompatibility complexHistocompatibility complexAlloreactive T cellsClass II determinantsPurified T cellsSpecific immune responseT cell responsivenessMixed lymphocyte cultureCell surface phenotypeStrains of miceBone marrow cellsState of activationStimulating antigenImmune responseBone donorsAntigen specificityBone marrowLymphocyte culturesSecondary exposurePrimed cellsResponding cellsAntigenBone
1989
Allograft incorporation: A biomechanical evaluation in a rat model
Pelker R, McKay J, Troiano N, Panjabi M, Friedlaender G. Allograft incorporation: A biomechanical evaluation in a rat model. Journal Of Orthopaedic Research® 1989, 7: 585-589. PMID: 2786956, DOI: 10.1002/jor.1100070417.Peer-Reviewed Original ResearchConceptsLewis ratsLevel of freezingImmunologic responseSprague-Dawley rat femursRat modelImmune responseAllogeneic boneFresh allograftsOsteosynthesis siteBiomechanical evaluationBiomechanical testingBiologic responseSubsequent healingAllograftsRat femurRatsIntact boneBoneFemurSignificant levelsResponseTransplantationTransplantGraftWeeks
1987
Immunologic Aspects of Bone Transplantation A Rationale for Future Studies
Horowitz M, Friedlaender G. Immunologic Aspects of Bone Transplantation A Rationale for Future Studies. Orthopedic Clinics Of North America 1987, 18: 227-233. PMID: 2951639, DOI: 10.1016/s0030-5898(20)30386-2.Peer-Reviewed Original Research
1986
Use of allogenic bone in hand injuries
Trumble T, Friedlaender G. Use of allogenic bone in hand injuries. Techniques In Orthopaedics 1986, 1: 79-83. DOI: 10.1097/00013611-198607000-00017.Peer-Reviewed Original ResearchAllogenic boneAllograft boneMultiple finger amputationsGiant cell tumorRisk of infectionDonor site morbidityCrush injuryFinger amputationsHand injuriesInternal fixationCell tumorsDistal radiusEarly motionSevere traumaMetacarpal defectsMetacarpal headAutogenous graftsGunshot woundsSite morbidityHand reconstructionInjuryAllograftsBone segmentsCortical boneBone
1983
FROZEN AND FREEZE-DRIED BONE GRAFTS
PELKER R, FRIEDLAENDER G, MARKHAM T. FROZEN AND FREEZE-DRIED BONE GRAFTS. Clinical Orthopaedics And Related Research® 1983, 174: 36-42. PMID: 6339142, DOI: 10.1097/00003086-198304000-00007.Peer-Reviewed Original Research
1976
The use of freeze-dried bone in middle-third face advancements
Epker B, Friedlaender G, Wolford L, West R. The use of freeze-dried bone in middle-third face advancements. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 1976, 42: 278-289. PMID: 787861, DOI: 10.1016/0030-4220(76)90161-4.Peer-Reviewed Original ResearchConceptsFreeze-dried bone allograftPrimary operative procedureFreeze-dried boneMedical Research InstituteNaval Medical Research InstituteSmall sequestrumAdditional surgeryOperative procedureClinical infectionBone allograftPatientsMaxillary areaAutogenous boneGraft materialInfectionTissue banksIntraoral exposureAllograftsBoneGraftMorbiditySequestrumComplicationsSurgeryOsteotomy