2003
Malignant bone tumors: limb sparing versus amputation.
DiCaprio MR, Friedlaender GE. Malignant bone tumors: limb sparing versus amputation. Journal Of The American Academy Of Orthopaedic Surgeons 2003, 11: 25-37. PMID: 12699369, DOI: 10.5435/00124635-200301000-00005.Peer-Reviewed Original ResearchConceptsLimb-sparing proceduresAppropriate surgical alternativesFunctional outcome studiesMainstay of treatmentExtent of diseaseAllograft-prosthetic compositeMalignant bone tumorsImportant outcome measureEffective chemotherapeutic agentLimb sparingMost patientsPatient ageReconstructed limbExpandable prosthesisSurgical alternativeTumor locationBone tumorsReconstructive surgeryOutcome measuresOutcome studiesSatisfactory functionModular endoprosthesesSurvival rateBone graftChemotherapeutic agents
1992
Immune responses to osteochondral allografts: nature and significance.
Friedlaender G, Horowitz M. Immune responses to osteochondral allografts: nature and significance. Orthopedics 1992, 15: 1171-5. PMID: 1409127, DOI: 10.3928/0147-7447-19921001-08.Peer-Reviewed Original ResearchConceptsImmune responseOsteochondral allograftsSuppressor/cytotoxic phenotypeBiologic significanceNumerous animal modelsT cell activationCell surface antigensMajor histocompatibility complexClinical resultsCytotoxic phenotypeBone allograftAnimal modelsSurface antigenBone graftAllograftsBiologic outcomesHistocompatibility complexCellular elementsGraftAntigenResponseImmunogenicitySignificanceBone graft and total hip arthroplasty A review
Huo M, Friedlaender G, Salvati E. Bone graft and total hip arthroplasty A review. The Journal Of Arthroplasty 1992, 7: 109-120. PMID: 1613516, DOI: 10.1016/0883-5403(92)90003-9.Peer-Reviewed Original Research
1987
Effects of Bone Graft and Electrical Stimulation on the Strength of Healing Bony Defects in Dogs
LINDSEY R, GROBMAN J, LEGGON R, PANJABI M, FRIEDLAENDER G. Effects of Bone Graft and Electrical Stimulation on the Strength of Healing Bony Defects in Dogs. Clinical Orthopaedics And Related Research® 1987, 222: 275-280. PMID: 3304757, DOI: 10.1097/00003086-198709000-00037.Peer-Reviewed Original ResearchConceptsElectrical stimulationGroup IIBone graftGroup IBony defectsGroup IIIAutogenous cancellous bone graftCancellous bone graftImplantable stimulatorTorsional strengthCanine femurStandard defectsIntact femurStrength 20Bone graftingGraftConclusive dataStrengthStimulationStrength 4WeeksHealing defectsFemurDefectsBiomechanical Aspects of Bone Autografts and Allografts
Pelker R, Friedlaender G. Biomechanical Aspects of Bone Autografts and Allografts. Orthopedic Clinics Of North America 1987, 18: 235-239. PMID: 3561975, DOI: 10.1016/s0030-5898(20)30387-4.Peer-Reviewed Original ResearchConceptsMechanical propertiesLarge torsional loadsLocal biomechanical environmentCompressive loadTorsional loadsFreeze-dried graftsFreeze-dried boneMechanical issuesBiomechanical responseLoadBiomechanical environmentBiomechanical aspectsBiomechanical perspectivePropertiesNormal biomechanicsFixation devicesBone graftDonor boneDevicesFrozen boneSkeletal reconstructionAllogeneic Bone in the Treatment of Tumors, Trauma, and Congenital Anomalies of the Hand
Trumble T, Friedlaender G. Allogeneic Bone in the Treatment of Tumors, Trauma, and Congenital Anomalies of the Hand. Orthopedic Clinics Of North America 1987, 18: 301-310. PMID: 3550577, DOI: 10.1016/s0030-5898(20)30393-x.Peer-Reviewed Original ResearchConceptsAllogeneic boneBone graftEarly motionAutogenous corticocancellous graftCongruent joint surfaceLarge osteochondral allograftsShorter hospital stayDonor site deficitMassive bone graftGraft donor sitesTubular graftSmall bone graftStrong cortical boneDonor siteAutogenous bone graftDonor site morbidityTreatment of tumorsHospital stayCortical graftsPediatric patientsFibular headHand therapyCorticocancellous graftHand injuriesInternal fixation
1983
FROZEN AND FREEZE-DRIED BONE GRAFTS
PELKER R, FRIEDLAENDER G, MARKHAM T. FROZEN AND FREEZE-DRIED BONE GRAFTS. Clinical Orthopaedics And Related Research® 1983, 174: 36-42. PMID: 6339142, DOI: 10.1097/00003086-198304000-00007.Peer-Reviewed Original ResearchImmune responses to osteochondral allografts. Current knowledge and future directions.
Friedlaender G. Immune responses to osteochondral allografts. Current knowledge and future directions. Clinical Orthopaedics And Related Research® 1983, 58-68. PMID: 6339143.Peer-Reviewed Original ResearchConceptsImmune responseReconstructive joint surgeryGraft recipientsAllograft immunogenicityAllograft successHistocompatibility antigensJoint surgeryAnimal modelsBone graftOsteochondral allograftsHuman recipientsBiomechanical factorsAllograftsImmunogenHeterogeneous cell typesPreliminary evidenceImmunogenicityRecipientsCell typesCurrent knowledgeMatter of speculationSkeletal tissuesTissuePotent sourceResponse