1992
Immune responses to osteochondral allografts: nature and significance.
Friedlaender G, Horowitz M. Immune responses to osteochondral allografts: nature and significance. Orthopedics 1992, 15: 1171-5. PMID: 1409127, DOI: 10.3928/0147-7447-19921001-08.Peer-Reviewed Original ResearchConceptsImmune responseOsteochondral allograftsSuppressor/cytotoxic phenotypeBiologic significanceNumerous animal modelsT cell activationCell surface antigensMajor histocompatibility complexClinical resultsCytotoxic phenotypeBone allograftAnimal modelsSurface antigenBone graftAllograftsBiologic outcomesHistocompatibility complexCellular elementsGraftAntigenResponseImmunogenicitySignificanceBone graft and total hip arthroplasty A review
Huo M, Friedlaender G, Salvati E. Bone graft and total hip arthroplasty A review. The Journal Of Arthroplasty 1992, 7: 109-120. PMID: 1613516, DOI: 10.1016/0883-5403(92)90003-9.Peer-Reviewed Original Research
1989
Allograft incorporation: A biomechanical evaluation in a rat model
Pelker R, McKay J, Troiano N, Panjabi M, Friedlaender G. Allograft incorporation: A biomechanical evaluation in a rat model. Journal Of Orthopaedic Research® 1989, 7: 585-589. PMID: 2786956, DOI: 10.1002/jor.1100070417.Peer-Reviewed Original ResearchConceptsLewis ratsLevel of freezingImmunologic responseSprague-Dawley rat femursRat modelImmune responseAllogeneic boneFresh allograftsOsteosynthesis siteBiomechanical evaluationBiomechanical testingBiologic responseSubsequent healingAllograftsRat femurRatsIntact boneBoneFemurSignificant levelsResponseTransplantationTransplantGraftWeeks
1987
Effects of Bone Graft and Electrical Stimulation on the Strength of Healing Bony Defects in Dogs
LINDSEY R, GROBMAN J, LEGGON R, PANJABI M, FRIEDLAENDER G. Effects of Bone Graft and Electrical Stimulation on the Strength of Healing Bony Defects in Dogs. Clinical Orthopaedics And Related Research® 1987, 222: 275-280. PMID: 3304757, DOI: 10.1097/00003086-198709000-00037.Peer-Reviewed Original ResearchConceptsElectrical stimulationGroup IIBone graftGroup IBony defectsGroup IIIAutogenous cancellous bone graftCancellous bone graftImplantable stimulatorTorsional strengthCanine femurStandard defectsIntact femurStrength 20Bone graftingGraftConclusive dataStrengthStimulationStrength 4WeeksHealing defectsFemurDefects
1984
Transplantation of Osteochondral Allografts
Friedlaender G, Mankin H. Transplantation of Osteochondral Allografts. Annual Review Of Medicine 1984, 35: 311-324. PMID: 6372659, DOI: 10.1146/annurev.me.35.020184.001523.Peer-Reviewed Original ResearchConceptsOsteochondral allograftsMassive osteochondral allograftsExcellent clinical resultsLimb-sparing approachesClinical resultsSkeletal deficitsBone tumorsImmune responseNeoplastic disordersCartilage graftsAllograftsSatisfactory tissueGraftEffective boneTransplantationLesionsTumorsInfectionAntigenBiological significanceStudies on the antigenicity of bone. II. Donor-specific anti-HLA antibodies in human recipients of freeze-dried allografts.
Friedlaender G, Strong D, Sell K. Studies on the antigenicity of bone. II. Donor-specific anti-HLA antibodies in human recipients of freeze-dried allografts. Journal Of Bone And Joint Surgery 1984, 66: 107-12. PMID: 6361041, DOI: 10.2106/00004623-198466010-00014.Peer-Reviewed Original ResearchConceptsDonor-specific anti-HLA antibodiesAnti-HLA antibodiesBone allograftImmune responseFreeze-dried bone allograftFreeze-dried allograftNinth patientAllograft donorsClinical eventsAllograftsPatientsHuman recipientsGraftAdverse effectsRecipientsAntibodiesMonthsBenign processSuch responsesResponseHLADonorsTissue types
1983
Biomechanical Properties of Bone Allografts
Pelker R, Friedlaender G, Markham T. Biomechanical Properties of Bone Allografts. Clinical Orthopaedics And Related Research® 1983, 174: 54-57. PMID: 6339144, DOI: 10.1097/00003086-198304000-00009.Peer-Reviewed Original ResearchConceptsOrthopaedic oncology serviceLow-grade tumorsPresence of recurrenceRelationship of complicationsMassachusetts General HospitalAllograft fractureOncology servicesAllograft implantationFunctional statusSkin sloughGeneral HospitalBone allograftIntramedullary rodFunctional restorationPatientsBenign conditionsResectionBone conditionsCadaveric segmentsComplicationsGraftBiomechanical propertiesTumorsMore yearsInfection
1981
Bone banking: current methods and suggested guidelines.
Friedlaender G, Mankin H. Bone banking: current methods and suggested guidelines. Instructional Course Lectures 1981, 30: 36-55. PMID: 6763618.Peer-Reviewed Original Research
1976
The use of freeze-dried bone in middle-third face advancements
Epker B, Friedlaender G, Wolford L, West R. The use of freeze-dried bone in middle-third face advancements. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 1976, 42: 278-289. PMID: 787861, DOI: 10.1016/0030-4220(76)90161-4.Peer-Reviewed Original ResearchConceptsFreeze-dried bone allograftPrimary operative procedureFreeze-dried boneMedical Research InstituteNaval Medical Research InstituteSmall sequestrumAdditional surgeryOperative procedureClinical infectionBone allograftPatientsMaxillary areaAutogenous boneGraft materialInfectionTissue banksIntraoral exposureAllograftsBoneGraftMorbiditySequestrumComplicationsSurgeryOsteotomy