2001
Evaluation of OP-1 as a Graft Substitute for Intertransverse Process Lumbar Fusion
Grauer J, Patel T, Erulkar J, Troiano N, Panjabi M, Friedlaender G. Evaluation of OP-1 as a Graft Substitute for Intertransverse Process Lumbar Fusion. Spine 2001, 26: 127-133. PMID: 11154530, DOI: 10.1097/00007632-200101150-00004.Peer-Reviewed Original ResearchConceptsIntertransverse process lumbar fusionIntertransverse process fusionManual palpationLumbar fusionOP-1Rabbit modelAutogenous iliac crest boneProcess fusionGraft substituteNew Zealand white rabbitsIliac crest boneOP-1 groupZealand white rabbitsMultidirectional flexibility testingAutograft specimensLess morbidityBiomechanical testing resultsCrest boneStudy groupAutograft groupBACKGROUND DATAFusion massWhite rabbitsL5-L6Bone graft substitute
1999
LONG-TERM FOLLOW-UP OF PATIENTS WITH OSTEOCHONDRAL ALLOGRAFTS A Correlation Between Immunologic Responses and Clinical Outcome
Friedlaender G, Strong D, Tomford W, Mankin H. LONG-TERM FOLLOW-UP OF PATIENTS WITH OSTEOCHONDRAL ALLOGRAFTS A Correlation Between Immunologic Responses and Clinical Outcome. Orthopedic Clinics Of North America 1999, 30: 583-588. PMID: 10471763, DOI: 10.1016/s0030-5898(05)70111-5.Peer-Reviewed Original ResearchConceptsClinical outcomesImmunologic responseHistocompatibility antigensLong-term clinical outcomesLong-term resultsFrozen bone allograftsPresence of sensitizationFrozen osteochondral allograftsImmune responseBone allograftAnimal modelsSatisfactory outcomeOsteochondral allograftsReconstructive alternativeClass IIBiologic successAllograftsOutcomesAntigenResponsePatientsHumansSensitization
1975
A laboratory model for the study of the immunobiology of osteosarcoma
Friedlaender G, Mitchell M. A laboratory model for the study of the immunobiology of osteosarcoma. Cancer 1975, 36: 1631-1639. PMID: 172215, DOI: 10.1002/1097-0142(197511)36:5<1631::aid-cncr2820360516>3.0.co;2-w.Peer-Reviewed Original ResearchConceptsCell-mediated immunityRegression of diseaseWistar-Lewis ratsMoloney sarcomasMoloney sarcoma virusProgressive diseaseClinical courseLung metastasesMicrocytotoxicity assayTreatment protocolImmune responseImmunologic similaritiesHuman osteosarcomaSerum factorsTumor cellsMarrow cavityOsteosarcomaTarget cellsRatsTumorsDiseaseSarcoma virusAnimalsWeeks of inoculationTissue culture