Immune Complex Deposition in Adult Male Sprague–Dawley Rats Chronically Immunized with GnRH
Vargas L, Sewell R, Marshall A, Galatioto J, Tsong Y, Catterall J, Hunnicutt G. Immune Complex Deposition in Adult Male Sprague–Dawley Rats Chronically Immunized with GnRH. American Journal Of Reproductive Immunology 2005, 54: 292-310. PMID: 16212651, DOI: 10.1111/j.1600-0897.2005.00310.x.Peer-Reviewed Original ResearchConceptsImmune complex depositionImmune complexesComplex depositionChronic immunizationAdult male Sprague-Dawley ratsMale Sprague-Dawley ratsAnti-GnRH antibodiesGlomerular immune complexesPotential deleterious side effectsSprague-Dawley ratsDeleterious side effectsIC depositionPathologic effectsSide effectsEffective immunocontraceptiveImmunizationFinal analysisOrgan analysisCellular damageRatsMost tissuesImmunofluorescence microscopyCellular levelAnimalsGnRH