2005
The Sept4 Septin Locus Is Required for Sperm Terminal Differentiation in Mice
Kissel H, Georgescu M, Larisch S, Manova K, Hunnicutt G, Steller H. The Sept4 Septin Locus Is Required for Sperm Terminal Differentiation in Mice. Developmental Cell 2005, 8: 353-364. PMID: 15737931, DOI: 10.1016/j.devcel.2005.01.021.Peer-Reviewed Original ResearchConceptsCaspase inhibitor XIAPDiverse cellular functionsDifferent cellular compartmentsInhibition of XIAPGenomic lociMutant spermCellular functionsMouse developmentMitochondrial architectureCellular compartmentsTumor suppressionTerminal differentiationSperm maturationDefective spermRing-like structureTargeted deletionResidual cytoplasmProteinMutant miceXIAPLociTail regionCytoplasmSpermCytokinesis
1997
Analysis of the Process of Localization of Fertilin to the Sperm Posterior Head Plasma Membrane Domain during Sperm Maturation in the Epididymis
Hunnicutt G, Koppel D, Myles D. Analysis of the Process of Localization of Fertilin to the Sperm Posterior Head Plasma Membrane Domain during Sperm Maturation in the Epididymis. Developmental Biology 1997, 191: 146-159. PMID: 9356178, DOI: 10.1006/dbio.1997.8700.Peer-Reviewed Original ResearchConceptsMembrane domainsSurface proteinsPlasma membraneHead domainSperm plasma membrane proteinsADAM protein familyPlasma membrane proteinsPlasma membrane domainsEgg plasma membraneSperm-egg fusionEntire sperm headPosterior headSperm surface moleculesFertilin betaProtein familyProtein localizationMembrane proteinsMetalloprotease domainFertilinDisintegrin domainLocalization patternsMature formSperm maturationProteolytic processingProtein