2005
Immune Complex Deposition in Adult Male Sprague–Dawley Rats Chronically Immunized with GnRH
Vargas L, Sewell R, Marshall A, Galatioto J, Tsong Y, Catterall J, Hunnicutt G. Immune Complex Deposition in Adult Male Sprague–Dawley Rats Chronically Immunized with GnRH. American Journal Of Reproductive Immunology 2005, 54: 292-310. PMID: 16212651, DOI: 10.1111/j.1600-0897.2005.00310.x.Peer-Reviewed Original ResearchConceptsImmune complex depositionImmune complexesComplex depositionChronic immunizationAdult male Sprague-Dawley ratsMale Sprague-Dawley ratsAnti-GnRH antibodiesGlomerular immune complexesPotential deleterious side effectsSprague-Dawley ratsDeleterious side effectsIC depositionPathologic effectsSide effectsEffective immunocontraceptiveImmunizationFinal analysisOrgan analysisCellular damageRatsMost tissuesImmunofluorescence microscopyCellular levelAnimalsGnRHThe Sept4 Septin Locus Is Required for Sperm Terminal Differentiation in Mice
Kissel H, Georgescu M, Larisch S, Manova K, Hunnicutt G, Steller H. The Sept4 Septin Locus Is Required for Sperm Terminal Differentiation in Mice. Developmental Cell 2005, 8: 353-364. PMID: 15737931, DOI: 10.1016/j.devcel.2005.01.021.Peer-Reviewed Original ResearchConceptsCaspase inhibitor XIAPDiverse cellular functionsDifferent cellular compartmentsInhibition of XIAPGenomic lociMutant spermCellular functionsMouse developmentMitochondrial architectureCellular compartmentsTumor suppressionTerminal differentiationSperm maturationDefective spermRing-like structureTargeted deletionResidual cytoplasmProteinMutant miceXIAPLociTail regionCytoplasmSpermCytokinesis
2001
Expression and Localization of Caveolin-1, and the Presence of Membrane Rafts, in Mouse and Guinea Pig Spermatozoa
Travis A, Merdiushev T, Vargas L, Jones B, Purdon M, Nipper R, Galatioto J, Moss S, Hunnicutt G, Kopf G. Expression and Localization of Caveolin-1, and the Presence of Membrane Rafts, in Mouse and Guinea Pig Spermatozoa. Developmental Biology 2001, 240: 599-610. PMID: 11784086, DOI: 10.1006/dbio.2001.0475.Peer-Reviewed Original ResearchConceptsMouse male germ cellsMale germ cellsCaveolin-1Membrane raftsDetergent-insoluble lipid raftsGerm cellsSimilar cellular functionsTrafficking of cholesterolImmunofluorescence analysisConfocal immunofluorescence analysisLight buoyant densityMembrane subdomainsGuinea pig spermatozoaSyntaxin 2Cellular functionsSucrose density gradient centrifugationFlagellar motilityLipid raftsIndirect immunofluorescence analysisNonraft fractionsSomatic cellsMembrane dynamicsAcrosomal biogenesisPig spermatozoaMature sperm