2021
Improved outcomes and staging in non-small-cell lung cancer guided by a molecular assay
Gupta AR, Woodard GA, Jablons DM, Mann MJ, Kratz JR. Improved outcomes and staging in non-small-cell lung cancer guided by a molecular assay. Future Oncology 2021, 17: 4785-4795. PMID: 34435876, PMCID: PMC9039775, DOI: 10.2217/fon-2021-0517.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkers, TumorCarcinogenesisCarcinoma, Non-Small-Cell LungChemotherapy, AdjuvantClinical Decision-MakingDatasets as TopicDisease-Free SurvivalGene Expression ProfilingGene Expression Regulation, NeoplasticHumansLung NeoplasmsMolecular Diagnostic TechniquesNeoplasm Recurrence, LocalNeoplasm StagingPneumonectomyProspective StudiesReal-Time Polymerase Chain ReactionRisk AssessmentConceptsCell lung cancerUndetectable metastasesLung cancerCell lung cancer patientsDisease-free survivalAdjuvant chemotherapy decisionsTime of surgeryLung cancer patientsSurgical resectionComplete resectionProspective studyCancer patientsChemotherapy decisionsResectionMolecular assaysPatientsPredictive benefitMetastasisCancerMortalityQuantitative PCRExpression profilesEarly stagesAssaysSurgery
2019
Mesothelioma: Scientific clues for prevention, diagnosis, and therapy
Carbone M, Adusumilli PS, Alexander HR, Baas P, Bardelli F, Bononi A, Bueno R, Felley‐Bosco E, Galateau‐Salle F, Jablons D, Mansfield AS, Minaai M, de Perrot M, Pesavento P, Rusch V, Severson DT, Taioli E, Tsao A, Woodard G, Yang H, Zauderer MG, Pass HI. Mesothelioma: Scientific clues for prevention, diagnosis, and therapy. CA A Cancer Journal For Clinicians 2019, 69: 402-429. PMID: 31283845, PMCID: PMC8192079, DOI: 10.3322/caac.21572.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Agents, ImmunologicalAsbestosAustraliaBiomarkers, TumorCarcinogenesisCombined Modality TherapyDiagnostic ErrorsEuropeGenetic Predisposition to DiseaseGerm-Line MutationGlobal Burden of DiseaseHumansIncidenceInhalation ExposureInternational CooperationMesotheliomaMolecular Targeted TherapyOccupational ExposurePleuraPleural NeoplasmsPneumonectomyPrognosisTumor Suppressor ProteinsUbiquitin ThiolesteraseUnited StatesConceptsNovel systemic treatmentsRole of surgeryKey pathogenic mechanismsAccuracy of diagnosisAggressive managementSystemic treatmentLocal therapyPeritoneal mesotheliomaPleural mesotheliomaMesothelioma incidenceIncidence rateTreatment outcomesProtein 1 mutationImmune responseGermline BRCA1Epidemiological studiesMortality ratePathogenic mechanismsMesotheliomaMesothelioma diagnosisUse of asbestosInadequate treatmentOlder individualsOlder peopleEarly detection