2001
PREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUS 8 (HHV-8) IN SAUDI ARABIAN PATIENTS WITH AND WITHOUT RENAL FAILURE1234
Almuneef M, Nimjee S, Khoshnood K, Miller G, Rigsby M. PREVALENCE OF ANTIBODIES TO HUMAN HERPESVIRUS 8 (HHV-8) IN SAUDI ARABIAN PATIENTS WITH AND WITHOUT RENAL FAILURE1234. Transplantation 2001, 71: 1120-1124. PMID: 11374413, DOI: 10.1097/00007890-200104270-00019.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseasePosttransplantation Kaposi's sarcomaPrevalence of antibodiesKaposi's sarcomaHuman herpesvirus 8HHV-8Renal diseaseHerpesvirus 8High incidenceHHV-8-seropositive individualsSmall viral capsid antigenHHV-8 infectionRenal transplant recipientsViral capsid antigenComparison groupArea of residenceSeronegative subjectsESRD patientsSeropositive subjectsTransplant recipientsCapsid antigenSerologic evidenceSeropositive individualsCommon cancerPatients
1998
High prevalence of antibodies to human herpesvirus-8 in relatives of patients with classic Kaposi's sarcoma from Sardinia
Cottoni F, Angeloni A, Heston L, Uccini S, Sirianni M, Masala M, Cerimele D, Rigsby M, Faggioni A, Miller G. High prevalence of antibodies to human herpesvirus-8 in relatives of patients with classic Kaposi's sarcoma from Sardinia. Journal Of The European Academy Of Dermatology And Venereology 1998, 11: s174. DOI: 10.1016/s0926-9959(98)95202-3.Peer-Reviewed Original ResearchHigh Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia
Angeloni A, Heston L, Uccini S, Sirianni M, Cottoni F, Masala M, Cerimele D, Lin S, Sun R, Rigsby M, Faggioni A, Miller G. High Prevalence of Antibodies to Human Herpesvirus 8 in Relatives of Patients with Classic Kaposi's Sarcoma from Sardinia. The Journal Of Infectious Diseases 1998, 177: 1715-1718. PMID: 9607855, DOI: 10.1086/517429.Peer-Reviewed Original ResearchConceptsSmall viral capsid antigenPrevalence of antibodiesClassic Kaposi's sarcomaHigh incidence areaKaposi's sarcomaActive HHV-8 infectionHuman herpesvirus type 8HHV-8 infectionViral capsid antigenRelatives of patientsHuman herpesvirus 8Familial risk factorsCapsid antigenRisk factorsHigh prevalenceKS patientsHerpesvirus 8SarcomaIncidence areaPopulation agesPatientsVertical transmissionPrevalenceAntibodiesType 8SEROLOGIC ASSOCIATION OF HUMAN HERPESVIRUS EIGHT WITH POSTTRANSPLANT KAPOSI'S SARCOMA IN SAUDI ARABIA1
Wajeh Q, Othman A, Khalid A, Lin3 4, Ren S, Lee H, Ross5 6, Rigsby7 8, Miller3 5. SEROLOGIC ASSOCIATION OF HUMAN HERPESVIRUS EIGHT WITH POSTTRANSPLANT KAPOSI'S SARCOMA IN SAUDI ARABIA1. Transplantation 1998, 65: 583-585. PMID: 9500639, DOI: 10.1097/00007890-199802270-00024.Peer-Reviewed Original ResearchConceptsPosttransplant Kaposi's sarcomaRenal transplant patientsKaposi's sarcomaTransplant patientsSmall viral capsid antigenRenal transplant recipientsTertiary care hospitalViral capsid antigenCross-sectional studyHHV8 antigensSerologic associationsTransplant recipientsRenal failureCare hospitalCapsid antigenCommon cancerControl subjectsSaudi ArabiaSeroreactivity ratesKS patientsSerologic resultsControl groupControl individualsPatientsSarcoma
1996
Antibodies to Butyrate-Inducible Antigens of Kaposi's Sarcoma–Associated Herpesvirus in Patients with HIV-1 Infection
Miller G, Rigsby M, Heston L, Grogan E, Sun R, Metroka C, Levy J, Gao S, Chang Y, Moore P. Antibodies to Butyrate-Inducible Antigens of Kaposi's Sarcoma–Associated Herpesvirus in Patients with HIV-1 Infection. New England Journal Of Medicine 1996, 334: 1292-1297. PMID: 8609946, DOI: 10.1056/nejm199605163342003.Peer-Reviewed Original ResearchConceptsHIV-1-infected patientsEpstein-Barr virusKaposi's sarcomaBC-1 cellsHuman immunodeficiency virus type 1 (HIV-1) infectionVirus type 1 infectionPositive serologic responseHIV-1 infectionType 1 infectionHigh-risk populationAntigen-positive cellsPresence of antibodiesPositive predictive valueEBV antigensKSHV antigensP40 antigenSerologic markersSerologic responseKaposi's Sarcoma-Associated HerpesvirusEtiologic roleSerologic testsPatientsSarcomaPredictive valueKSHV infection
1992
Detection of Epstein‐Barr virus in the brain by the polymerase chain reaction
Pedneault L, Katz B, Miller G. Detection of Epstein‐Barr virus in the brain by the polymerase chain reaction. Annals Of Neurology 1992, 32: 184-192. PMID: 1324632, DOI: 10.1002/ana.410320210.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusEBV DNAPolymerase chain reactionRole of EBVChain reactionCentral nervous system syndromeDiverse neurological syndromesKidney transplant recipientsHerpes group virusesTransplant recipientsMetabolic encephalopathiesBrain biopsyImmunodeficiency syndromeNeurological syndromeImmunodeficient hostsEBV genomeBrain specimensViral isolationPatientsGroup virusesSerological testsSyndromeBrainVirusEncephalitis
1986
Primary central nervous system lymphoma related to Epstein‐Barr virus in a patient with acquired immune deficiency syndrome
Rosenberg N, Hochberg F, Miller G, Kleinschmidt‐DeMasters B. Primary central nervous system lymphoma related to Epstein‐Barr virus in a patient with acquired immune deficiency syndrome. Annals Of Neurology 1986, 20: 98-102. PMID: 3017188, DOI: 10.1002/ana.410200118.Peer-Reviewed Original ResearchConceptsCentral nervous system lymphomaEpstein-Barr virus infectionNervous system lymphomaImmune deficiency syndromeSystem lymphomaDeficiency syndromeVirus infectionPrimary central nervous system lymphomaEpstein-Barr virus genomeEpstein-Barr virusCentral nervous systemPrimary lymphomaNervous systemTumor tissueLymphomaPatientsSyndromeInfectionAcid preparationsHybridization studiesDeoxyribonucleic acid preparationsVirus genomeK fragment
1985
Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1.
Rowe D, Heston L, Metlay J, Miller G. Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 7429-7433. PMID: 2997790, PMCID: PMC391358, DOI: 10.1073/pnas.82.21.7429.Peer-Reviewed Original ResearchConceptsChronic active EBV infectionActive EBV infectionEpstein-Barr virusJijoye strainEBV infectionEBV DNACertain patientsP3HR-1Human antiseraVirus strainsNuclear antigenHr-1JijoyeVirus deletion mutantsLtk- cellsMouse Ltk- cellsImmortalization processPatientsGene transferNeoantigensLymphocytesInfectionAntigen1119 INFECTION WITH MULTIPLE EB VIRUS (EBV) GENOTYPES IN AN INFANT WITH AIDS AND HIS MOTHER
Katz B, Andiman W, Miller G. 1119 INFECTION WITH MULTIPLE EB VIRUS (EBV) GENOTYPES IN AN INFANT WITH AIDS AND HIS MOTHER. Pediatric Research 1985, 19: 297-297. DOI: 10.1203/00006450-198504000-01149.Peer-Reviewed Original ResearchEB virusEBV genotypesPeripheral bloodHigh-risk groupPatients' peripheral bloodDifferent EBV isolatesSingle-cell subclonesCNS lymphomaSevere complicationsEBV strainsAIDS patientsImmunocompetent hostsEBV genomeMother's bloodEBV isolatesLymphoblastoid cell linesBiopsy tissueSimultaneous infectionVertical transmissionInfantsInfectionAIDSBloodMothersPatientsAntibody Responses to Two Epstein-Barr Virus Nuclear Antigens Defined by Gene Transfer
Miller G, Grogan E, Fischer D, Niederman J, Schooley R, Henle W, Lenoir G, Liu C. Antibody Responses to Two Epstein-Barr Virus Nuclear Antigens Defined by Gene Transfer. New England Journal Of Medicine 1985, 312: 750-755. PMID: 2983211, DOI: 10.1056/nejm198503213121204.Peer-Reviewed Original ResearchConceptsChronic active EBV infectionActive EBV infectionEBV infectionNuclear antigenEpstein-Barr virus nuclear antigenEpstein-Barr virus DNAEBV-seropositive subjectsAbnormal immune responseAssociation of EBVNorth African patientsAbsence of antibodiesSuch patientsAfrican patientsSerologic studiesImmune responseNasopharyngeal carcinomaLymphoid cellsPatientsViral gene productsSpecific viral gene productsViral mutationsSerologic reactionsAntigenSerum samplesM antigenEpstein-Barr Virus Genomes Are Restricted to Secondary Neoplastic Cells Following Bone Marrow Transplantation
Schubach W, Miller G, Thomas E. Epstein-Barr Virus Genomes Are Restricted to Secondary Neoplastic Cells Following Bone Marrow Transplantation. Blood 1985, 65: 535-538. DOI: 10.1182/blood.v65.3.535.535.Peer-Reviewed Original ResearchBone marrow transplantationEpstein-Barr virusMarrow transplantationB-cell neoplasmsEBV genomeCell neoplasmsEpstein-Barr virus genomeLong-term remissionGroup of patientsCells of patientsEngrafted lymphocytesMononuclear bloodRecurrent leukemiaSecondary neoplasmsMononuclear cellsOriginal leukemiaPatient categoriesNeoplastic cellsPatientsTumor cellsTransplantationNeoplasmsLeukemiaCellsVirus genome
1982
Biology of Lymphoid Cells Transformed by Epstein—Barr Virus
Robinson J, Miller G. Biology of Lymphoid Cells Transformed by Epstein—Barr Virus. The Viruses 1982, 151-207. DOI: 10.1007/978-1-4684-4163-5_4.Peer-Reviewed Original ResearchInfectious mononucleosisBurkitt's lymphomaLymphoblastoid cell linesContinuous lymphoblastoid cell linesEpstein-Barr virusSubsequent electron microscopic examinationBL tissuesBL tumorsElectron microscopic examinationLymphoid cellsHerpesvirus groupNormal individualsLymphoid linesFraction of cellsPatientsViral particlesCell linesVirus particlesCellsMononucleosisLymphomaMalignancyTumors
1981
Genome of a mononucleosis epstein-barr virus contains DNA fragments previously regarded to be unique to Burkitt's lymphoma isolates
Fischer D, Miller G, Gradoville L, Heston L, Weststrate M, Maris W, Wright J, Brandsma J, Summers W. Genome of a mononucleosis epstein-barr virus contains DNA fragments previously regarded to be unique to Burkitt's lymphoma isolates. Cell 1981, 24: 543-553. PMID: 6263500, DOI: 10.1016/0092-8674(81)90345-7.Peer-Reviewed Original ResearchConceptsBurkitt's lymphomaB95-8Infectious mononucleosisUncomplicated infectious mononucleosisEpstein-Barr virusSalivary isolatesEBV infectionDisease manifestationsLymphomaMononucleosisPatientsEBVRestriction enzyme analysisVirusMajor insertionC fragmentEnzyme analysisHr-1IsolatesInfectionDeletionAvailable virus
1979
SITE OF EPSTEIN-BARR VIRUS REPLICATION IN THE OROPHARYNX
Morgan DG, Miller G, Niederman J, Smith HW, Dowaliby JM. SITE OF EPSTEIN-BARR VIRUS REPLICATION IN THE OROPHARYNX. The Lancet 1979, 314: 1154-1157. PMID: 91888, DOI: 10.1016/s0140-6736(79)92384-5.Peer-Reviewed Original ResearchConceptsInfectious Epstein-Barr virusEpstein-Barr virus replicationAcute infectious mononucleosisEpstein-Barr virusInfectious mononucleosisPatient's virusThroat washingsViral antigensEBV productionTonsillar lymphocytesInfectious virusVirus replicationParotid secretionPatientsCell-free formSalivary glandsOropharynxVirusSecretionCell-free materialSalivaMononucleosisCellsTonsillectomyLymphocytes
1976
Infectious Mononucleosis — Epstein–Barr-Virus Shedding in Saliva and the Oropharynx
Niederman J, Miller G, Pearson H, Pagano J, Dowaliby J. Infectious Mononucleosis — Epstein–Barr-Virus Shedding in Saliva and the Oropharynx. New England Journal Of Medicine 1976, 294: 1355-1359. PMID: 177872, DOI: 10.1056/nejm197606172942501.Peer-Reviewed Original ResearchConceptsThroat washingsDuct orificeEpstein-Barr virusDemonstration of virusOropharyngeal sitesInfectious mononucleosisOropharyngeal specimensThird monthIntermittent excretionExcretion patternsAge groupsSecond weekVirusPatientsMonthsOral secretionsSalivaMononucleosisOropharynxExcretionSwabsSecretionWeeks
1974
OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS
Siegel N, Strauch B, Andrews L, Miller G, Cook C. OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS. Pediatric Research 1974, 8: 428-428. DOI: 10.1203/00006450-197404000-00531.Peer-Reviewed Original ResearchEpstein-Barr virusRenal homograftsImmunosuppressive agentsImmunosuppressive drugsHuman umbilical cord leukocytesRenal transplant recipientsLatent EBV infectionEBV capsid antigenEBV nuclear antigenUmbilical cord leukocytesRate of excretionOropharyngeal excretionEBV infectionImmunosuppressive therapySeropositive patientsTransplant recipientsCapsid antigenThroat washingsVirus 8Chronic uremiaThroat samplesHealthy controlsPatientsExcretion rateExcretionOROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY RENAL TRANSPLANT RECIPIENTS AND OTHER PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS
Strauch B, Siegel N, Andrews L, Miller G. OROPHARYNGEAL EXCRETION OF EPSTEIN-BARR VIRUS BY RENAL TRANSPLANT RECIPIENTS AND OTHER PATIENTS TREATED WITH IMMUNOSUPPRESSIVE DRUGS. The Lancet 1974, 303: 234-237. PMID: 4130246, DOI: 10.1016/s0140-6736(74)92546-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAntibodies, ViralAzathioprineCarrier StateChildChild, PreschoolFemaleFluorescent Antibody TechniqueHerpesvirus 4, HumanHumansImmunity, CellularImmunosuppressive AgentsKidney TransplantationLeukocytesMaleMiddle AgedMouthMucusPharynxPostoperative CarePrednisoneProspective StudiesTherapeutic IrrigationTransplantation, HomologousConceptsEpstein-Barr virusImmunosuppressive drugsRenal homograftsRenal transplant recipientsOropharyngeal excretionShed virusVirus excretorsImmunosuppressive therapySeropositive patientsTransplant recipientsChronic uraemiaThroat washingsVirus 8Seropositive individualsThroat samplesVirus sheddingVirus infectionPatientsNuclear antigenHealthy staffLong-term proliferationDrugsVirusHomograftsTransplantation
1973
Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis
Miller G, Niederman J, Andrews L. Prolonged Oropharyngeal Excretion of Epstein–Barr Virus after Infectious Mononucleosis. New England Journal Of Medicine 1973, 288: 229-232. PMID: 4345064, DOI: 10.1056/nejm197302012880503.Peer-Reviewed Original ResearchConceptsEpstein-Barr virusThroat washesInfectious mononucleosisEpstein-Barr viral antigensEpstein-Barr virus antibodiesInfectious mononucleosis syndromeUmbilical cord leukocytesOropharyngeal excretionClinical symptomsControl subjectsSerum antibodiesVirus antibodiesViral antigensBlood leukocytesSuch antigensComplement fixationContinuous cell linesFactor presentMononucleosisAntibodiesReference seraPatientsCell linesSyndromeLeukocytes
1972
Prospective study of Epstein-Barr virusinfections in acute lymphoblastic leukemia of childhood
Miller G, Shope T, Heston L, O'Brien R, Schwartz A, Pearson H. Prospective study of Epstein-Barr virusinfections in acute lymphoblastic leukemia of childhood. The Journal Of Pediatrics 1972, 80: 932-937. PMID: 4337277, DOI: 10.1016/s0022-3476(72)80004-0.Peer-Reviewed Original ResearchConceptsEBV antibodiesProspective studyLymphoblastoid cell linesAcutelymphoblastic leukemiaEpstein-Barr virus infectionAntibody-positive childrenAntibody-negative patientsEBV antibody titersAcute lymphoblastic leukemiaCourse of leukemiaCell linesEBV infectionInfectious mononucleosisUntreated patientsMaternal antibodiesCongenital leukemiaSerologic evidenceAntibody titersLymphoblastic leukemiaVirus infectionPatientsLeukemiaProgressive declineEBVUndetectable levels