1997
The Locus of Epstein–Barr Virus Terminal Repeat Processing Is Bound with Enhanced Affinity by Sp1 and Sp3
Spain T, Sun R, Miller G. The Locus of Epstein–Barr Virus Terminal Repeat Processing Is Bound with Enhanced Affinity by Sp1 and Sp3. Virology 1997, 237: 137-147. PMID: 9344916, DOI: 10.1006/viro.1997.8770.Peer-Reviewed Original ResearchConceptsRecombination eventsRepeat binding proteinMinimal binding siteAntibody supershift assaysRepeat processingSp1 sitesCellular proteinsLarge internal repeatRecombinogenic regionsInternal repeatsSp1Supershift assaysRecombinant proteinsTerminal repeatBinding proteinLytic cycle inductionEBV lytic cycle inductionCycle inductionProteinAffinity of bindingBinding sitesRepeatsSite 1DNASp3The transcriptional activator Sp1, a novel autoantigen
Spain T, Sun R, Gradzka M, Lin S, Craft J, Miller G. The transcriptional activator Sp1, a novel autoantigen. Arthritis & Rheumatism 1997, 40: 1085-1095. PMID: 9182919, DOI: 10.1002/art.1780400613.Peer-Reviewed Original ResearchConceptsTranscriptional activator Sp1Novel autoantigenComplex of DNAGC-rich sequencesActivator Sp1Undifferentiated connective tissue diseaseSp1 proteinTranscription activatorConnective tissue diseaseExtractable nuclear antigensEpstein-Barr virusSp1Nuclear extractsCellular DNAMalar rashAntinuclear antibodiesClinical characteristicsProteinDNARaynaud's phenomenonTissue diseaseAutoantigenic proteinsAutoimmune seraElectrophoretic mobilityAutoantigens
1991
Heterodimers of the Zebra and Fos Basic Domains Bind DNA with the Specificity of Zebra
Taylor N, Kolman J, Miller G. Heterodimers of the Zebra and Fos Basic Domains Bind DNA with the Specificity of Zebra. Experimental Biology And Medicine 1991, 99-103. DOI: 10.1007/978-1-4612-0405-3_15.Peer-Reviewed Original Research
1990
Inhibition of specific binding of EBNA 1 to DNA by Murine Monoclonal and certain human polyclonal antibodies
Orlowski R, Polvino-Bodnar M, Hearing J, Miller G. Inhibition of specific binding of EBNA 1 to DNA by Murine Monoclonal and certain human polyclonal antibodies. Virology 1990, 176: 638-642. PMID: 2161154, DOI: 10.1016/0042-6822(90)90036-q.Peer-Reviewed Original ResearchConceptsEBNA-1 proteinGel mobility shift experimentsMobility shift experimentsSequence-specific DNARecognition of DNAEBNA-1Binding of DNASpecific bindingLac promoterDNA bindingMonoclonal antibodiesDimerization siteSpecific DNANonfusion proteinBurkitt's lymphoma cellsShift experimentsMolecular massEscherichia coliProteinDNASame monoclonal antibodyBindingPolyclonal antibodiesEB virusLymphoma cells
1989
Role of The Zebra Protein in the Switch Between Epstein-Barr Virus Latency and Replication
Miller G, Talyor N, Countryman J, Rooney C, Katz D, Kolman J, Jenson H, Grogan E, Gradoville L. Role of The Zebra Protein in the Switch Between Epstein-Barr Virus Latency and Replication. Experimental Biology And Medicine 1989, 17-35. DOI: 10.1007/978-1-4612-4508-7_2.Peer-Reviewed Original ResearchEarly genesCell backgroundCell linesDNA binding proteinTranscriptional activatorGenome rearrangementsGenome configurationZEBRA expressionEBV late genesLate genesViral genesAutostimulatory loopGenesBinding proteinMarmoset cell linesEBV early genesAgent TPAPermissive cellsZEBRA proteinDefective virusZebraEpstein-Barr virus latencyBZLF1 geneExpressionProtein