2001
CD4+ T-Cell Effectors Inhibit Epstein-Barr Virus-Induced B-Cell Proliferation
Nikiforow S, Bottomly K, Miller G. CD4+ T-Cell Effectors Inhibit Epstein-Barr Virus-Induced B-Cell Proliferation. Journal Of Virology 2001, 75: 3740-3752. PMID: 11264363, PMCID: PMC114865, DOI: 10.1128/jvi.75.8.3740-3752.2001.Peer-Reviewed Original ResearchMeSH KeywordsAdultB-LymphocytesCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell DivisionCell SizeCells, CulturedEpstein-Barr Virus InfectionsEpstein-Barr Virus Nuclear AntigensFlow CytometryHerpesvirus 4, HumanHumansImmunologic MemoryLymphocyte CountReceptors, IgESerologyTacrolimusT-Lymphocyte SubsetsConceptsEpstein-Barr virusB cell proliferationT cellsB cellsB-cell lymphoproliferative diseaseRemoval of CD4Effector T cellsMemory T cellsT cell effectorsT cell surveillanceCytolytic T cellsEarly proliferative phaseCell linesImmune controlLymphoproliferative diseaseImmunodeficient hostsImmune surveillanceLymphoblastoid cell linesCD4Proliferative phaseImmortalized cell linesCD8CD23VirusInfection
1990
Inhibition of specific binding of EBNA 1 to DNA by Murine Monoclonal and certain human polyclonal antibodies
Orlowski R, Polvino-Bodnar M, Hearing J, Miller G. Inhibition of specific binding of EBNA 1 to DNA by Murine Monoclonal and certain human polyclonal antibodies. Virology 1990, 176: 638-642. PMID: 2161154, DOI: 10.1016/0042-6822(90)90036-q.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, MonoclonalAntibodies, ViralAntigens, ViralBurkitt LymphomaCell NucleusDNA, ViralEpstein-Barr Virus Nuclear AntigensHerpesvirus 4, HumanHumansMiceOligonucleotide ProbesTumor Cells, CulturedConceptsEBNA-1 proteinGel mobility shift experimentsMobility shift experimentsSequence-specific DNARecognition of DNAEBNA-1Binding of DNASpecific bindingLac promoterDNA bindingMonoclonal antibodiesDimerization siteSpecific DNANonfusion proteinBurkitt's lymphoma cellsShift experimentsMolecular massEscherichia coliProteinDNASame monoclonal antibodyBindingPolyclonal antibodiesEB virusLymphoma cellsTopological Effects of EBNA 1 on oriP
Orlowski R, Miller G. Topological Effects of EBNA 1 on oriP. Advances In Experimental Medicine And Biology 1990, 278: 115-124. PMID: 1963028, DOI: 10.1007/978-1-4684-5853-4_12.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalAntigens, ViralBase SequenceBinding SitesDeoxyribonuclease IV (Phage T4-Induced)DNA, SuperhelicalDNA, ViralEndodeoxyribonucleasesEpstein-Barr Virus Nuclear AntigensEscherichia coliEscherichia coli ProteinsGenes, ViralHerpesvirus 4, HumanMolecular Sequence DataNucleic Acid ConformationPlasmidsRecombinant ProteinsRepetitive Sequences, Nucleic AcidTransformation, Bacterial
1987
Novel nuclear antigens recognized by human sera in lymphocytes latently infected by Epstein-Barr virus
Rowe D, Farrell P, Miller G. Novel nuclear antigens recognized by human sera in lymphocytes latently infected by Epstein-Barr virus. Virology 1987, 156: 153-162. PMID: 3027963, DOI: 10.1016/0042-6822(87)90446-6.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, ViralCell NucleusEpstein-Barr Virus Nuclear AntigensHerpesvirus 4, HumanHumansLymphocytesMolecular WeightConceptsEBNA seraAntigen complexX50-7Immortalization of lymphocytesEpstein-Barr virusEBNA INovel nuclear antigenIV groupNew antigensNuclear antigenLymphocytesCell clonesWestern immunoblottingSerumCell linesEBVAntigenMolecular weight proteinsHuman serumHigh molecular weight proteinsRajiVirusViral genomeGroupWeight proteins
1985
Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1.
Rowe D, Heston L, Metlay J, Miller G. Identification and expression of a nuclear antigen from the genomic region of the Jijoye strain of Epstein-Barr virus that is missing in its nonimmortalizing deletion mutant, P3HR-1. Proceedings Of The National Academy Of Sciences Of The United States Of America 1985, 82: 7429-7433. PMID: 2997790, PMCID: PMC391358, DOI: 10.1073/pnas.82.21.7429.Peer-Reviewed Original ResearchConceptsChronic active EBV infectionActive EBV infectionEpstein-Barr virusJijoye strainEBV infectionEBV DNACertain patientsP3HR-1Human antiseraVirus strainsNuclear antigenHr-1JijoyeVirus deletion mutantsLtk- cellsMouse Ltk- cellsImmortalization processPatientsGene transferNeoantigensLymphocytesInfectionAntigenAntibody Responses to Two Epstein-Barr Virus Nuclear Antigens Defined by Gene Transfer
Miller G, Grogan E, Fischer D, Niederman J, Schooley R, Henle W, Lenoir G, Liu C. Antibody Responses to Two Epstein-Barr Virus Nuclear Antigens Defined by Gene Transfer. New England Journal Of Medicine 1985, 312: 750-755. PMID: 2983211, DOI: 10.1056/nejm198503213121204.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntibodies, ViralAntibody FormationAntigens, ViralCapsid ProteinsCell NucleusChildChronic DiseaseDNA, RecombinantEpstein-Barr Virus Nuclear AntigensHerpesviridae InfectionsHerpesvirus 4, HumanHumansNasopharyngeal NeoplasmsConceptsChronic active EBV infectionActive EBV infectionEBV infectionNuclear antigenEpstein-Barr virus nuclear antigenEpstein-Barr virus DNAEBV-seropositive subjectsAbnormal immune responseAssociation of EBVNorth African patientsAbsence of antibodiesSuch patientsAfrican patientsSerologic studiesImmune responseNasopharyngeal carcinomaLymphoid cellsPatientsViral gene productsSpecific viral gene productsViral mutationsSerologic reactionsAntigenSerum samplesM antigen
1984
Regions of the EBV genome involved in latency and lymphocyte immortalization.
Miller G. Regions of the EBV genome involved in latency and lymphocyte immortalization. Medical Virology 1984, 30: 107-28. PMID: 6087408.Peer-Reviewed Original ResearchAnimalsAntigens, ViralB-LymphocytesCell NucleusCell Transformation, ViralChildChild, PreschoolChromosome DeletionDNA, ViralEpstein-Barr Virus Nuclear AntigensFemaleGenes, ViralHerpesvirus 4, HumanHumansLymphomaMaleRepetitive Sequences, Nucleic AcidRNA, ViralTranscription, GeneticTumor Virus InfectionsVirionVirus Replication