2024
Cytomorphological characteristics of low‐grade papillary urothelial carcinoma in voided urine samples: Distinction from benign and high‐grade papillary urothelial carcinoma
Takeda K, Adeniran A, Levi A, Tang H, Cai G. Cytomorphological characteristics of low‐grade papillary urothelial carcinoma in voided urine samples: Distinction from benign and high‐grade papillary urothelial carcinoma. Cytopathology 2024, 35: 724-732. PMID: 38992916, DOI: 10.1111/cyt.13413.Peer-Reviewed Original ResearchHigh-grade papillary urothelial carcinomaLow-grade papillary urothelial carcinomaPapillary urothelial carcinomaUrothelial carcinomaVoided urine samplesCytomorphologic featuresBenign casesUrine samplesUrine specimensNuclear enlargementVoided urine specimensHigh-grade transformationNuclear-to-cytoplasmic (N/CIrregular nuclear membranesUrine cytologyRetrospective reviewHistopathological diagnosisCytomorphologic characteristicsCytomorphological distinctionFrequent recurrenceCytologic featuresCarcinomaBenign conditionsAccurate diagnosisHigh N/C ratio
2023
Respiratory Tract
Sardana R, Cai G. Respiratory Tract. 2023, 189-215. DOI: 10.1007/978-3-031-44289-6_11.Peer-Reviewed Original ResearchRespiratory tractNeedle aspirationKey cytomorphologic featuresCommon inflammatory conditionSpectrum of diagnosesTransbronchial needle aspirationFine-needle aspirationFalse-negative diagnosesBronchoalveolar lavageClinical symptomsBronchial washPulmonary pathologyInflammatory conditionsRespiratory cytologyBrush smearsCytomorphologic featuresCytological evaluationCytologic specimensInfectious diseasesDiagnosisTractDiagnostic processAspirationInitial investigationLavageLiver and Biliary Tract
Wang X, Cai G. Liver and Biliary Tract. 2023, 247-266. DOI: 10.1007/978-3-031-44289-6_14.Peer-Reviewed Original ResearchBiliary tractPrimary sclerosis cholangitisExtrahepatic biliary tractRelevant clinical historyEchinococcal cystsLiver cystsAmebic abscessClinical historyNonneoplastic lesionsNonneoplastic disordersCytomorphologic featuresBenign lesionsSolid lesionsHepatocyte hyperplasiaMalignant counterpartsInfectious entitiesLesionsCystsLiverTractCholangitisCirrhosisAbscessStentingHyperplasia
2022
Intraductal papillary neoplasm of the bile duct: Cytomorphologic and molecular features
Stendahl K, Gilani SM, Basturk O, Hui P, Sigel C, Cai G. Intraductal papillary neoplasm of the bile duct: Cytomorphologic and molecular features. Cancer Cytopathology 2022, 131: 37-49. PMID: 36041224, PMCID: PMC9812877, DOI: 10.1002/cncy.22637.Peer-Reviewed Original ResearchConceptsIntraductal papillary neoplasmBile ductCytomorphologic featuresFine granular chromatinPapillary neoplasmVacuolated cytoplasmGranular chromatinCase of IPNBColumnar cellsComplex papillary architectureOriginal cytological diagnosisCommon bile ductCharacteristic cytomorphologic featuresHigh-grade dysplasiaMolecular featuresBackground mucinKRAS testingHepatic ductRetrospective studyAcute inflammationHistopathologic confirmationKRAS mutationsPapillary architecturePapillary clustersCytological diagnosis
2019
- Metastatic tumorsLiver lesionsCore needle biopsyFine-needle aspirationHepatocyte lesionsPrimary tumorDefinite diagnosisDiagnostic challengeNeedle biopsyAncillary studiesHepatocellular carcinomaNeedle aspirationCytomorphologic featuresDiagnostic pitfallsLesion lesionsLesionsCytological featuresTumorsBiopsyMorphologic comparisonCholangiocarcinomaCarcinomaLiverDiagnosis
- Lung lesionsNon-small cell carcinomaNon-hematopoietic tumorsMediastinal lymph nodesFine-needle aspirationLymph nodesCell carcinomaHematopoietic lesionsNeedle aspirationCytomorphologic featuresDiagnostic pitfallsMolecular testingLesionsAppropriate specimen triageSpecimen triageSite evaluationBiopsyCarcinomaLungTumorsTriage
2018
Diagnosis of Infectious Diseases in the Lower Respiratory Tract: A Cytopathologist's Perspective
Baldassarri RJ, Kumar D, Baldassarri S, Cai G. Diagnosis of Infectious Diseases in the Lower Respiratory Tract: A Cytopathologist's Perspective. Archives Of Pathology & Laboratory Medicine 2018, 143: 683-694. PMID: 30203986, DOI: 10.5858/arpa.2017-0573-ra.BooksConceptsLower respiratory tract infectionsRespiratory tract infectionsLower respiratory tractRespiratory tractTract infectionsCommon organismDifferential diagnosisCytomorphologic featuresInfectious diseasesGeneral clinical characteristicsOrganism identificationClinical characteristicsImmunosuppressed patientsRespiratory cytologyAncillary testingCausative organismClinical informationConfident diagnosisAncillary testsPubMed searchInfectious agentsAccurate diagnosisDiagnosisInfectionAncillary methods
2013
Performance of endoscopic ultrasound-guided fine needle aspiration in diagnosing pancreatic neuroendocrine tumors
Bernstein J, Ustun B, Alomari A, Bao F, Aslanian HR, Siddiqui U, Chhieng D, Cai G. Performance of endoscopic ultrasound-guided fine needle aspiration in diagnosing pancreatic neuroendocrine tumors. CytoJournal 2013, 10: 10. PMID: 23858320, PMCID: PMC3709383, DOI: 10.4103/1742-6413.112648.Peer-Reviewed Original ResearchEndoscopic ultrasound-guided fine-needle aspirationPancreatic neuroendocrine tumorsUltrasound-guided fine-needle aspirationFine-needle aspirationNeuroendocrine tumorsNeedle aspirationCytological diagnosisMucinous cystic neoplasmSmall-sized tumorsDiagnosis of neoplasmRetrospective studyCystic neoplasmsRare tumorDefinite diagnosisDifferential diagnosisSized tumorsFNA diagnosisCytomorphologic featuresAtypical diagnosisDiagnostic pitfallsPatientsDiscrepant casesTumorsImmunocytochemical studyDiagnosis
2012
Cytoplasmic vacuolization: An under‐recognized cytomorphologic feature in endocrine tumors of the pancreas
Levy GH, Finkelstein A, Harigopal M, Chhieng D, Cai G. Cytoplasmic vacuolization: An under‐recognized cytomorphologic feature in endocrine tumors of the pancreas. Diagnostic Cytopathology 2012, 41: 623-628. PMID: 22807461, DOI: 10.1002/dc.22893.Peer-Reviewed Original ResearchConceptsFine-needle aspirationPancreatic endocrine neoplasmsCytomorphologic featuresDiagnostic pitfallsEndoscopic ultrasound-guided fine-needle aspirationUltrasound-guided fine-needle aspirationFine cytoplasmic vacuolesClinicopathologic featuresDiagnostic challengeEndocrine tumorsEndocrine neoplasmsSmall biopsiesAccurate diagnosisImmunocytochemical studyCytoplasmic vacuoles
2011
The cytomorphologic spectrum of salivary gland type tumors in the lung and mediastinum: A report of 16 patients
Monaco SE, Khalbuss WE, Ustinova E, Liang A, Cai G. The cytomorphologic spectrum of salivary gland type tumors in the lung and mediastinum: A report of 16 patients. Diagnostic Cytopathology 2011, 40: 1062-1070. PMID: 21591276, DOI: 10.1002/dc.21733.Peer-Reviewed Original ResearchConceptsSalivary gland-type tumorsMucoepidermoid carcinomaPrimary tumorType tumorsPolymorphous low-grade adenocarcinomaCommon histological subtypeAspiration cytology specimensDiagnosis of ACCSalivary duct carcinomaLow-grade adenocarcinomaMinor salivary glandsCytomorphologic spectrumDuct carcinomaHistological subtypesBasaloid tumorsCystic carcinomaCytomorphologic featuresSoft palateGrade adenocarcinomaDiagnostic pitfallsNasal cavityCytology casesCytology specimensMediastinumTumors