2015
Immunomodulatory activity of nivolumab in metastatic renal cell carcinoma (mRCC): Association of biomarkers with clinical outcomes.
Choueiri T, Fishman M, Escudier B, McDermott D, Kluger H, Stadler W, Perez-Gracia J, McNeel D, Curti B, Harrison M, Plimack E, Appleman L, Fong L, Drake C, Young T, Chasalow S, Ross-Macdonald P, Simon J, Walker D, Sznol M. Immunomodulatory activity of nivolumab in metastatic renal cell carcinoma (mRCC): Association of biomarkers with clinical outcomes. Journal Of Clinical Oncology 2015, 33: 4500-4500. DOI: 10.1200/jco.2015.33.15_suppl.4500.Peer-Reviewed Original Research
2014
Prognostic and predictive tumor-based biomarkers in patients (pts) with advanced renal cell carcinoma (RCC) treated with interferon alpha (IFN) with or without bevacizumab (Bev): Results from CALGB (Alliance) 90206.
Kluger H, Halabi S, Solomon N, Jilaveanu L, Zito C, Sznol J, Nixon A, Rini B, Small E, George D. Prognostic and predictive tumor-based biomarkers in patients (pts) with advanced renal cell carcinoma (RCC) treated with interferon alpha (IFN) with or without bevacizumab (Bev): Results from CALGB (Alliance) 90206. Journal Of Clinical Oncology 2014, 32: 4532-4532. DOI: 10.1200/jco.2014.32.15_suppl.4532.Peer-Reviewed Original ResearchImmunomodulatory activity of nivolumab in previously treated and untreated metastatic renal cell carcinoma (mRCC): Biomarker-based results from a randomized clinical trial.
Choueiri T, Fishman M, Escudier B, Kim J, Kluger H, Stadler W, Perez-Gracia J, McNeel D, Curti B, Harrison M, Plimack E, Appleman L, Fong L, Drake C, Cohen L, Srivastava S, Jure-Kunkel M, Hong Q, Kurland J, Sznol M. Immunomodulatory activity of nivolumab in previously treated and untreated metastatic renal cell carcinoma (mRCC): Biomarker-based results from a randomized clinical trial. Journal Of Clinical Oncology 2014, 32: 5012-5012. DOI: 10.1200/jco.2014.32.15_suppl.5012.Peer-Reviewed Original Research
2012
Drug targets and predictive biomarkers in the management of metastatic melanoma
Thumar J, Giesen E, Kluger HM. Drug targets and predictive biomarkers in the management of metastatic melanoma. Pharmacogenomics And Personalized Medicine 2012, Volume 5: 139-148. PMID: 23226069, PMCID: PMC3513235, DOI: 10.2147/pgpm.s25100.Peer-Reviewed Original ResearchMetastatic melanomaPredictive biomarkersApproval of ipilimumabChoice of treatmentImmune system characteristicsFederal Drug AdministrationClinical benefitTherapeutic optionsFatal skin cancerTreatment strategiesDrug combinationsMelanoma treatmentPromising drugAntitumor effectsDrug AdministrationSkin cancerIndividual tumorsMelanomaPersonalized therapyTherapyTreatmentDrug targetsBiomarkersIpilimumabTumors