2017
Microvessel density as a prognostic marker in high-risk renal cell carcinoma.
Weiss S, Puligandla M, Jilaveanu L, Haas N, Wang X, Zito C, Boeke M, Neumeister V, Manola J, DiPaola R, Kluger H. Microvessel density as a prognostic marker in high-risk renal cell carcinoma. Journal Of Clinical Oncology 2017, 35: 4565-4565. DOI: 10.1200/jco.2017.35.15_suppl.4565.Peer-Reviewed Original ResearchHigher microvessel densityRenal cell carcinomaDisease-free survivalHigh-risk renal cell carcinomaOverall survivalMicrovessel densityTreatment armsEntire cohortCell carcinomaNephrectomy specimensGrade I/IIVascular endothelial growth factor (VEGF) pathwayStratified log-rank testEndothelial growth factor pathwayClear cell renal cell carcinomaImproved overall survivalCell renal cell carcinomaClear cell histologyShorter overall survivalLog-rank testTumor microvessel densityAbsence of necrosisGrowth factor pathwaysAdjuvant sunitinibImproved OS
2014
PD-L1 Expression in Clear Cell Renal Cell Carcinoma: An Analysis of Nephrectomy and Sites of Metastases
Jilaveanu LB, Shuch B, Zito CR, Parisi F, Barr M, Kluger Y, Chen L, Kluger HM. PD-L1 Expression in Clear Cell Renal Cell Carcinoma: An Analysis of Nephrectomy and Sites of Metastases. Journal Of Cancer 2014, 5: 166-172. PMID: 24563671, PMCID: PMC3931264, DOI: 10.7150/jca.8167.Peer-Reviewed Original ResearchPD-L1 expressionMetastatic sitesPD-L1Tissue microarrayMetastatic specimensTumor PD-L1 expressionClear cell renal cell carcinomaPD-1 inhibitorsAutomated Quantitative AnalysisMetastatic RCC patientsCell renal cell carcinomaSite of metastasisRenal cell carcinomaClear cell RCCRenal cell carcinoma cellsInter-tumor heterogeneityRCC patientsCell carcinomaNephrectomy specimensTumor expressionCore biopsyImmune escapeCell RCCBiopsy coresClinical development