2020
High WHO/ISUP Grade and Unfavorable Architecture, Rather Than Typing of Papillary Renal Cell Carcinoma, May Be Associated With Worse Prognosis
Yang C, Shuch B, Kluger H, Humphrey PA, Adeniran AJ. High WHO/ISUP Grade and Unfavorable Architecture, Rather Than Typing of Papillary Renal Cell Carcinoma, May Be Associated With Worse Prognosis. The American Journal Of Surgical Pathology 2020, 44: 582-593. PMID: 32101890, DOI: 10.1097/pas.0000000000001455.Peer-Reviewed Original ResearchConceptsPapillary renal cell carcinomaType 2 papillary renal cell carcinomaDisease-free survivalWHO/ISUP gradeHigh WHO/ISUP gradeOverall survivalRenal cell carcinomaISUP gradeWorld Health OrganizationPRCC typeType 1Hazard ratioPathologic stageCell carcinomaMicropapillary architectureHistologic parametersType 2Stepwise multivariate Cox regression analysisWorse disease-free survivalMultivariate Cox regression analysisTumor areaType 1 histologyUrological Pathology (ISUP) gradeCox regression analysisMixed type 1
2015
Clinicopathological and immunohistochemical characteristics of papillary renal cell carcinoma with emphasis on subtyping
Alomari AK, Nettey OS, Singh D, Kluger H, Adeniran AJ. Clinicopathological and immunohistochemical characteristics of papillary renal cell carcinoma with emphasis on subtyping. Human Pathology 2015, 46: 1418-1426. PMID: 26239624, DOI: 10.1016/j.humpath.2015.06.006.Peer-Reviewed Original ResearchConceptsPapillary renal cell carcinomaType 2 tumorType 1 tumorsRenal cell carcinomaImmunohistochemical profileType 1Fat invasionCell carcinomaType 2Main renal vein invasionType 2 papillary renal cell carcinomaRenal sinus fat invasionNuclear grade 3Similar immunohistochemical profilePerinephric fat invasionRenal vein invasionSinus fat invasionNuclear grade 2High nuclear gradeSubtypes of PRCCExcellent prognosisAngiolymphatic invasionClinicopathological featuresLong followRenal vein