2013
Ulcer, gastric surgery and pancreatic cancer risk: an analysis from the International Pancreatic Cancer Case–Control Consortium (PanC4)
Bosetti C, Lucenteforte E, Bracci PM, Negri E, Neale RE, Risch HA, Olson SH, Gallinger S, Miller AB, Bueno-de-Mesquita HB, Talamini R, Polesel J, Ghadirian P, Baghurst PA, Zatonski W, Fontham E, Holly EA, Gao YT, Yu H, Kurtz RC, Cotterchio M, Maisonneuve P, Zeegers MP, Duell EJ, Boffetta P, La Vecchia C. Ulcer, gastric surgery and pancreatic cancer risk: an analysis from the International Pancreatic Cancer Case–Control Consortium (PanC4). Annals Of Oncology 2013, 24: 2903-2910. PMID: 23970016, PMCID: PMC3811904, DOI: 10.1093/annonc/mdt336.Peer-Reviewed Original ResearchConceptsPancreatic cancer riskPancreatic Cancer Case-Control ConsortiumCancer riskPeptic ulcerOdds ratioInternational Pancreatic Cancer Case-Control ConsortiumMultivariable logistic regression modelHistory of gastrectomyHistory of ulcerCancer diagnosisH2-receptor antagonistsProton pump inhibitorsCase-control studyPancreatic cancer casesSummary odds ratiosLogistic regression modelsLarge collaborative studiesGastric surgeryPharmacological treatmentExcess riskCancer surveillancePancreatic cancerCancer casesGastrectomyUlcers
2011
A Population-Based Case-Control Study of Occupational Exposure to Acids and the Risk of Lung Cancer: Evidence for Specificity of Association
Soskolne CL, Jhangri GS, Scott HM, Brenner DR, Siemiatycki J, Lakhani R, Gérin M, Dewar R, Miller AB, Risch HA. A Population-Based Case-Control Study of Occupational Exposure to Acids and the Risk of Lung Cancer: Evidence for Specificity of Association. International Journal Of Occupational And Environmental Health 2011, 17: 1-8. PMID: 21344813, DOI: 10.1179/oeh.2011.17.1.1.Peer-Reviewed Original ResearchConceptsCase-control studyLung cancerOccupational exposurePopulation-based case-control studySmoking-adjusted odds ratiosStrong inorganic acid mistsCancer-specific riskOverall lung cancerLifetime occupational historyLung cancer casesConditional logistic regressionInorganic acid mistsBorough of residenceExcess riskEffect modificationOdds ratioCancer casesSecondary data analysisOccupational historyCancer effectsLifetime exposureLogistic regressionCancerConfidence intervalsExposure assessment
2000
BRCA1 and BRCA2 Mutation Analysis of 208 Ashkenazi Jewish Women with Ovarian Cancer
Moslehi R, Chu W, Karlan B, Fishman D, Risch H, Fields A, Smotkin D, Ben-David Y, Rosenblatt J, Russo D, Schwartz P, Tung N, Warner E, Rosen B, Friedman J, Brunet J, Narod S. BRCA1 and BRCA2 Mutation Analysis of 208 Ashkenazi Jewish Women with Ovarian Cancer. American Journal Of Human Genetics 2000, 66: 1259-1272. PMID: 10739756, PMCID: PMC1288193, DOI: 10.1086/302853.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBRCA2 ProteinBreast NeoplasmsDNA Mutational AnalysisFemaleFounder EffectGene FrequencyGenes, BRCA1Genetic Predisposition to DiseaseHumansIncidenceIsraelJewsMaleMiddle AgedMutationNeoplasm ProteinsNeoplasm StagingNorth AmericaOvarian NeoplasmsPedigreeTranscription FactorsConceptsFemale first-degree relativesAge 75 yearsOvarian cancerFirst-degree relativesBreast cancerAshkenazi Jewish womenHereditary breast-ovarian cancer syndromeBreast-ovarian cancer syndromeObserved excess riskFounder mutationFamilial cancer riskDetailed family historyBRCA2 mutation analysisCumulative incidenceExcess riskHealthy controlsRelative riskFamily historyMedical CenterCancer riskCancer syndromesAshkenazi Jewish populationControl populationProtein truncation testBRCA2 genes
1989
Mortality from Breast Cancer after Irradiation during Fluoroscopic Examinations in Patients Being Treated for Tuberculosis
Miller A, Howe G, Sherman G, Lindsay J, Yaffe M, Dinner P, Risch H, Preston D. Mortality from Breast Cancer after Irradiation during Fluoroscopic Examinations in Patients Being Treated for Tuberculosis. New England Journal Of Medicine 1989, 321: 1285-1289. PMID: 2797101, DOI: 10.1056/nejm198911093211902.Peer-Reviewed Original ResearchConceptsBreast cancerRelative riskFluoroscopic examinationRadiation-induced breast cancerFirst exposureLinear dose-response relationUse of mammographyYears of ageDose-response relationNumber of deathsTherapeutic pneumothoraxAsymptomatic womenExcess riskLifetime riskAdditive riskCancerWomenSubstantial proportionSmall benefitAgeRadiation dosesRiskTuberculosisMortalityExposure