2013
Genital Powder Use and Risk of Ovarian Cancer: A Pooled Analysis of 8,525 Cases and 9,859 Controls
Terry KL, Karageorgi S, Shvetsov YB, Merritt MA, Lurie G, Thompson PJ, Carney ME, Weber RP, Akushevich L, Lo-Ciganic WH, Cushing-Haugen K, Sieh W, Moysich K, Doherty JA, Nagle CM, Berchuck A, Pearce CL, Pike M, Ness RB, Webb PM, Study A, Rossing M, Schildkraut J, Risch H, Goodman M. Genital Powder Use and Risk of Ovarian Cancer: A Pooled Analysis of 8,525 Cases and 9,859 Controls. Cancer Prevention Research 2013, 6: 811-821. PMID: 23761272, PMCID: PMC3766843, DOI: 10.1158/1940-6207.capr-13-0037.Peer-Reviewed Original ResearchConceptsEpithelial ovarian cancerOvarian cancerPowder usePopulation-based case-control studyMost histologic subtypesEpithelial ovarian cancer riskBorderline serous tumorsOvarian cancer riskCase-control studySubtype-specific riskConditional logistic regressionHistologic subtypeHistologic typeSerous tumorsPotential confoundersPooled analysisPooled ORsModifiable exposuresCancer riskTumor behaviorEpidemiologic investigationsCancerLogistic regressionLifetime numberCarcinogenic effectsRecent alcohol consumption and risk of incident ovarian carcinoma: a pooled analysis of 5,342 cases and 10,358 controls from the Ovarian Cancer Association Consortium
Kelemen LE, Bandera EV, Terry KL, Rossing MA, Brinton LA, Doherty JA, Ness RB, Kjær S, Chang-Claude J, Köbel M, Lurie G, Thompson PJ, Carney ME, Moysich K, Edwards R, Bunker C, Jensen A, Høgdall E, Cramer DW, Vitonis AF, Olson SH, King M, Chandran U, Lissowska J, Garcia-Closas M, Yang H, Webb PM, Schildkraut JM, Goodman MT, Risch HA, , on behalf of the Australian Ovarian Cancer Study Group and Australian Cancer Study (Ovarian Cancer), and on behalf of the Ovarian Cancer Association Consortium. Recent alcohol consumption and risk of incident ovarian carcinoma: a pooled analysis of 5,342 cases and 10,358 controls from the Ovarian Cancer Association Consortium. BMC Cancer 2013, 13: 28. PMID: 23339562, PMCID: PMC3568733, DOI: 10.1186/1471-2407-13-28.Peer-Reviewed Original ResearchConceptsOvarian carcinomaOvarian Cancer Association ConsortiumHistologic typeAlcohol intakeBorderline tumorsOdds ratioClear cell ovarian carcinomaOz/dModerate alcohol drinkingTumor histologic typeSpecific histologic typesCase-control studyConfidence intervalsRecent alcohol intakeRecent alcohol consumptionAverage daily intakeModifiable causesMucinous histologySmoking statusAlcohol drinkingStatistical heterogeneityOC casesRisk associationAlcohol consumptionDeadly cancer
2010
Genetic Variation in the Prostate Stem Cell Antigen Gene and Upper Gastrointestinal Cancer in White Individuals
Lochhead P, Frank B, Hold GL, Rabkin CS, Ng MT, Vaughan TL, Risch HA, Gammon MD, Lissowska J, Weck MN, Raum E, Müller H, Illig T, Klopp N, Dawson A, McColl KE, Brenner H, Chow W, El–Omar E. Genetic Variation in the Prostate Stem Cell Antigen Gene and Upper Gastrointestinal Cancer in White Individuals. Gastroenterology 2010, 140: 435-441. PMID: 21070776, PMCID: PMC3031760, DOI: 10.1053/j.gastro.2010.11.001.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAntigens, NeoplasmCarcinoma, Squamous CellCase-Control StudiesEsophageal NeoplasmsFemaleGastritis, AtrophicGastrointestinal NeoplasmsGenetic Predisposition to DiseaseGPI-Linked ProteinsHelicobacter InfectionsHelicobacter pyloriHumansMaleNeoplasm ProteinsPolymorphism, Single NucleotideRiskWhite PeopleConceptsChronic atrophic gastritisNoncardia gastric cancerUpper gastrointestinal cancerGastric cancer casesProstate stem cell antigen (PSCA) geneCancer casesGastric cancerAtrophic gastritisGastrointestinal cancerRs2294008 polymorphismWhite individualsRisk allelesHelicobacter pylori-infected subjectsPylori-infected subjectsPopulation-based studySquamous cell carcinomaGastric cancer patientsGastric cardia cancerCase-control studyEsophageal cancer casesDiffuse histologic typeAntigen geneProximal cancersGastric atrophyHistologic type
2002
Histopathologic Features of Genetically Determined Ovarian Cancer
Shaw P, McLaughlin J, Zweemer R, Narod S, Risch H, Verheijen R, Ryan A, Menko F, Kenemans P, Jacobs I. Histopathologic Features of Genetically Determined Ovarian Cancer. International Journal Of Gynecological Pathology 2002, 21: 407-411. PMID: 12352190, DOI: 10.1097/00004347-200210000-00011.Peer-Reviewed Original ResearchConceptsInvasive serous carcinomasOvarian carcinomaSilverberg gradeGermline mutationsHistologic typeSerous carcinomaNuclear gradeGOG grade 3High histologic gradeBRCA1/BRCA2Serous histologyGynecologic pathologistsHistologic featuresHistopathologic featuresBRCA carriersHistologic gradeBRCA mutationsOvarian cancerArchitectural gradeBRCA2 mutationsGrade 3Germline BRCA1CarcinomaMutation statusControl group
2000
Multiple Births and Risk of Epithelial Ovarian Cancer
Whiteman D, Murphy M, Cook L, Cramer D, Hartge P, Marchbanks P, Nasca P, Ness R, Purdie D, Risch H. Multiple Births and Risk of Epithelial Ovarian Cancer. Journal Of The National Cancer Institute 2000, 92: 1172-1177. PMID: 10904091, DOI: 10.1093/jnci/92.14.1172.Peer-Reviewed Original ResearchConceptsEpithelial ovarian cancerParous womenOvarian cancerMultiple birthsCase patientsOdds ratioMultivariable logistic regression analysisNonmucinous ovarian cancerOral contraceptive useSummary odds ratiosLogistic regression analysisNonmucinous tumorsMucinous tumorsHistologic typeTumor histologyControl womenInvasive tumorsRelative riskReproductive factorsContraceptive useOvarian carcinogenesisLower riskCancerAvailable evidenceTumors
1996
Differences in Risk Factors for Epithelial Ovarian Cancer by Histologic Type
Risch H, Marrett L, Jain M, Howe G. Differences in Risk Factors for Epithelial Ovarian Cancer by Histologic Type. American Journal Of Epidemiology 1996, 144: 363-372. PMID: 8712193, DOI: 10.1093/oxfordjournals.aje.a008937.Peer-Reviewed Original ResearchConceptsEpithelial ovarian cancerMucinous tumorsNonmucinous tumorsOvarian cancerHistologic typeOdds ratioPrimary epithelial ovarian cancerUnconditional logistic regression methodsInvasive serous cancerMucinous ovarian tumorsOral contraceptive useFull-term pregnancyRisk factor associationsCase-control studyOral contraceptivesSerous cancerEndometrioid cancerNoncontraceptive estrogensFat intakeInvasive cancerOvarian tumorsRisk factorsEpithelial tumorsReproductive factorsContraceptive use