GalNAc-Specific Soybean Lectin Inhibits HIV Infection of Macrophages through Induction of Antiviral Factors
Zhou R, Wang X, Liu H, Guo L, Su Q, Wang H, Vasiliadis T, Ho W, Li J. GalNAc-Specific Soybean Lectin Inhibits HIV Infection of Macrophages through Induction of Antiviral Factors. Journal Of Virology 2018, 92: 10.1128/jvi.01720-17. PMID: 29263266, PMCID: PMC5827391, DOI: 10.1128/jvi.01720-17.Peer-Reviewed Original ResearchConceptsMannose-binding lectinHIV infectionT cellsInterferon-stimulated genesMitogenic effectAntiviral factorsHIV agentsAttachment of HIVAntiviral interferon-stimulated genesActivation of CD4Suppression of HIVDose-dependent fashionGlycosylated envelope proteinsAnti-HIV activityGroups of macrophagesC chemokinesCoreceptor CCR5HIV gp120HIV microbicidesBeta interferonHIVClinical settingCD4InfectionMacrophages