2016
Fusion proteins in head and neck neoplasms: Clinical implications, genetics, and future directions for targeting
Escalante D, Wang H, Fundakowski C. Fusion proteins in head and neck neoplasms: Clinical implications, genetics, and future directions for targeting. Cancer Biology & Therapy 2016, 17: 995-1002. PMID: 27636353, PMCID: PMC5079396, DOI: 10.1080/15384047.2016.1219823.Peer-Reviewed Original ResearchNeck neoplasmsClinical implicationsTyrosine kinase inhibitor dasatinibCell lung cancerTreatment of headChronic myeloid leukemiaBCR-ABL fusionKinase inhibitor dasatinibLung cancerNovel fusion proteinHematologic malignanciesMyeloid leukemiaMidline headSolid neoplasmsDiagnostic targetingNeoplasmsInhibitor dasatinibFusion proteinDiagnostic opportunitiesBiological behaviorSalivary glandsTherapeutic triumphsNeck structuresMalignancyPathogenesis
2014
Expression of ERCC1, TYMS, RRM1, TUBB3, non-muscle myosin II, myoglobin and MyoD1 in lung adenocarcinoma pleural effusions predicts survival in patients receiving platinum-based chemotherapy
JIANG H, WANG H, WANG S, PEI Z, FU Z, FANG C, WANG J, LU Q, WANG E, LI J. Expression of ERCC1, TYMS, RRM1, TUBB3, non-muscle myosin II, myoglobin and MyoD1 in lung adenocarcinoma pleural effusions predicts survival in patients receiving platinum-based chemotherapy. Molecular Medicine Reports 2014, 11: 3523-3532. PMID: 25573098, DOI: 10.3892/mmr.2014.3141.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma of LungAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorDNA-Binding ProteinsDrug Resistance, NeoplasmEndonucleasesFemaleGene ExpressionHumansImmunohistochemistryKaplan-Meier EstimateLung NeoplasmsMaleMiddle AgedMyoD ProteinMyoglobinMyosin Type IIPlatinumPleural Effusion, MalignantPrognosisRibonucleoside Diphosphate ReductaseThymidylate SynthaseTubulinTumor Suppressor ProteinsConceptsExcision repair cross-complementing gene 1Expression of ERCC1Platinum-based chemotherapyMetastatic lung adenocarcinomaLung adenocarcinomaPleural effusionLung Adenocarcinoma Pleural EffusionsPlatinum-based chemotherapy treatmentTumor cellsUntreated lung adenocarcinomasSurvival of patientsMalignant pleural effusionPleural fluid samplesExpression levelsProtein expression levelsWestern blot analysisClinical outcomesPatient survivalLung cancerChemotherapy treatmentLung carcinomaNon-muscle myosin IIPatientsAdenocarcinomaSurvival rateLearning curve for endobronchial ultrasound-guided transbronchial needle aspiration: Experience of a community-based teaching hospital
WANG H, D’CRUZ C, YAM D, DILLA L, TSANG P. Learning curve for endobronchial ultrasound-guided transbronchial needle aspiration: Experience of a community-based teaching hospital. Molecular Medicine Reports 2014, 10: 2441-2446. PMID: 25189939, DOI: 10.3892/mmr.2014.2533.Peer-Reviewed Original ResearchConceptsEndobronchial ultrasound-guided transbronchial needle aspirationUltrasound-guided transbronchial needle aspirationTransbronchial needle aspirationEBUS-TBNACell blocksTissue diagnosisNeedle aspirationHistological examinationTTF-1Community-based teaching hospitalAcid-fast bacilli stainMetastatic lung carcinomaSquamous cell carcinomaThyroid transcription factor-1KRAS mutation analysisSubsequent tissue diagnosisSufficient diagnostic materialCell block preparationsLymph nodesMetastatic adenocarcinomaMediastinal lymphomaCell carcinomaNodal stagingLung cancerTranscription factor 1