Pulmonary vasculopathy in explanted lungs from patients with interstitial lung disease undergoing lung transplantation
Dotan Y, Stewart J, Gangemi A, Wang H, Aneja A, Chakraborty B, Dass C, Zhao H, Marchetti N, D'Alonzo G, Cordova FC, Criner G, Mamary AJ. Pulmonary vasculopathy in explanted lungs from patients with interstitial lung disease undergoing lung transplantation. BMJ Open Respiratory Research 2020, 7: e000532. PMID: 32661103, PMCID: PMC7359183, DOI: 10.1136/bmjresp-2019-000532.Peer-Reviewed Original ResearchConceptsFibrotic interstitial lung diseaseMean pulmonary artery pressureRight heart catheterisationInterstitial lung diseaseAdvanced fibrotic interstitial lung diseasesPulmonary arterial vasculopathySevere pulmonary hypertensionPulmonary hypertensionArterial vasculopathyLung transplantationLung diseaseEnd-stage interstitial lung diseaseSeverity of PHModerate pulmonary hypertensionPulmonary artery pressureIdiopathic pulmonary hypertensionIdiopathic pulmonary fibrosisHuman lung tissueArtery pressureHeart catheterisationPlexiform lesionsAdult patientsIntimal fibrosisPulmonary fibrosisLung diffusion