2020
Pulmonary vasculopathy in explanted lungs from patients with interstitial lung disease undergoing lung transplantation
Dotan Y, Stewart J, Gangemi A, Wang H, Aneja A, Chakraborty B, Dass C, Zhao H, Marchetti N, D'Alonzo G, Cordova FC, Criner G, Mamary AJ. Pulmonary vasculopathy in explanted lungs from patients with interstitial lung disease undergoing lung transplantation. BMJ Open Respiratory Research 2020, 7: e000532. PMID: 32661103, PMCID: PMC7359183, DOI: 10.1136/bmjresp-2019-000532.Peer-Reviewed Original ResearchConceptsFibrotic interstitial lung diseaseMean pulmonary artery pressureRight heart catheterisationInterstitial lung diseaseAdvanced fibrotic interstitial lung diseasesPulmonary arterial vasculopathySevere pulmonary hypertensionPulmonary hypertensionArterial vasculopathyLung transplantationLung diseaseEnd-stage interstitial lung diseaseSeverity of PHModerate pulmonary hypertensionPulmonary artery pressureIdiopathic pulmonary hypertensionIdiopathic pulmonary fibrosisHuman lung tissueArtery pressureHeart catheterisationPlexiform lesionsAdult patientsIntimal fibrosisPulmonary fibrosisLung diffusion
2018
Inflammatory signature in lung tissues in patients with combined pulmonary fibrosis and emphysema
Cornwell WD, Kim C, Lastra AC, Dass C, Bolla S, Wang H, Zhao H, Ramsey FV, Marchetti N, Rogers TJ, Criner GJ. Inflammatory signature in lung tissues in patients with combined pulmonary fibrosis and emphysema. Biomarkers 2018, 24: 232-239. PMID: 30411980, PMCID: PMC6509019, DOI: 10.1080/1354750x.2018.1542458.Peer-Reviewed Original ResearchConceptsInterstitial pulmonary fibrosisInflammatory profilePulmonary fibrosisLung tissueInflammatory proteinDistinct inflammatory profilesCohort of patientsCombined pulmonary fibrosisDistinct inflammatory processesEmphysematous lung tissueInflammatory protein levelsExplanted LungsInflammatory signatureInflammatory processDisease processEmphysemaPatientsEmphysematous tissueFibrosisLungProtein levelsTissue sectionsCPFETissueTissue extracts