2019
Primary salivary gland‐type tumors of the tracheobronchial tree diagnosed by transbronchial fine needle aspiration: Clinical and cytomorphologic features with histopathologic correlation
Doxtader EE, Shah AA, Zhang Y, Wang H, Dyhdalo KS, Farver C. Primary salivary gland‐type tumors of the tracheobronchial tree diagnosed by transbronchial fine needle aspiration: Clinical and cytomorphologic features with histopathologic correlation. Diagnostic Cytopathology 2019, 47: 1168-1176. PMID: 31343850, DOI: 10.1002/dc.24285.Peer-Reviewed Original ResearchConceptsSalivary gland-type tumorsTransbronchial fine needle aspirationPrimary salivary gland-type tumorsFine-needle aspirationTracheobronchial treeSalivary gland tumorsNeedle aspirationCytomorphologic featuresGland tumorsSalivary gland-type neoplasmsPrimary salivary gland tumorsSurgical pathology specimenClear cell carcinomaCorresponding surgical specimenAdenoid cystic carcinomaEpithelial-myoepithelial carcinomaSurgical pathology specimensSalivary gland typeEndobronchial biopsyFrequent diagnosisStudy cohortLung massTracheal massCell carcinomaCytomorphologic changesApplication of the Milan System for Reporting Submandibular Gland Cytopathology: An international, multi‐institutional study
Maleki Z, Baloch Z, Lu R, Shafique K, Song SJ, Viswanathan K, Rao RA, Lefler H, Fatima A, Wiles A, Jo VY, Wang H, Fadda G, Powers CN, Ali SZ, Pantanowitz L, Siddiqui MT, Nayar R, Klijanienko J, Barkan GA, Krane JF, Rossi ED, Callegari F, Kholová I, Bongiovanni M, Faquin WC, Pusztaszeri MP. Application of the Milan System for Reporting Submandibular Gland Cytopathology: An international, multi‐institutional study. Cancer Cytopathology 2019, 127: 306-315. PMID: 31050186, PMCID: PMC7404554, DOI: 10.1002/cncy.22135.Peer-Reviewed Original ResearchAdolescentAdultAgedAged, 80 and overAlgorithmsBiopsy, Fine-NeedleChildChild, PreschoolCytodiagnosisFemaleFollow-Up StudiesHealth FacilitiesHumansInfantInternational AgenciesMaleMedical RecordsMiddle AgedPrecancerous ConditionsRetrospective StudiesRisk AssessmentSalivary Gland NeoplasmsSubmandibular GlandYoung Adult
2017
“Suspicious” salivary gland FNA: Risk of malignancy and interinstitutional variability
Maleki Z, Miller JA, Arab SE, Fadda G, Bo P, Wise O, Rossi ED, Jhala N, Ashish C, Ali SZ, Wang H. “Suspicious” salivary gland FNA: Risk of malignancy and interinstitutional variability. Cancer Cytopathology 2017, 126: 94-100. PMID: 29053216, DOI: 10.1002/cncy.21939.Peer-Reviewed Original ResearchConceptsRisk of malignancySalivary gland FNAsFNA specimensExact testSuspicious casesFine needle aspiration cytologyEpithelial metaplastic changesSignificant interinstitutional variabilityTertiary medical centerFisher's exact testSalivary gland neoplasmsSalivary gland lesionsSFM categoryMetaplastic changesMalignancy categoryConclusive diagnosisMalignant tumorsAspiration cytologyMedical CenterFNA casesIndeterminate resultsSFM groupGland neoplasmsSpecific neoplasmsGland lesions“Atypical” salivary gland fine needle aspiration: Risk of malignancy and interinstitutional variability
Wang H, Malik A, Maleki Z, Rossi ED, Ping B, Chandra A, Ali SZ, Fadda G, Wang J, Arab SE, Zhao H, Jhala N. “Atypical” salivary gland fine needle aspiration: Risk of malignancy and interinstitutional variability. Diagnostic Cytopathology 2017, 45: 1088-1094. PMID: 28960946, DOI: 10.1002/dc.23826.Peer-Reviewed Original ResearchConceptsRisk of malignancyFine-needle aspirationSalivary gland fine-needle aspirationMalignant tumorsNeedle aspirationTertiary medical centerSalivary gland lesionsHistological resectionSalivary Gland CytopathologyBenign tumorsMedical CenterAtypical diagnosisBenign neoplasmsBenign lesionsFNA yieldGland lesionsInterinstitutional variabilityDiagnostic categoriesMorphologic heterogeneityDiagnosisTumorsMilan SystemVariable practiceMalignancyLesions
2016
FNA biopsy of secondary nonlymphomatous malignancies in salivary glands: A multi‐institutional study of 184 cases
Wang H, Hoda R, Faquin W, Rossi E, Hotchandani N, Sun T, Pusztaszeri M, Bizzarro T, Bongiovanni M, Patel V, Jhala N, Fadda G, Gong Y. FNA biopsy of secondary nonlymphomatous malignancies in salivary glands: A multi‐institutional study of 184 cases. Cancer Cytopathology 2016, 125: 91-103. PMID: 28001329, DOI: 10.1002/cncy.21798.Peer-Reviewed Original ResearchConceptsFine-needle aspiration biopsySquamous cell carcinomaDefinitive diagnosisDiagnostic challengeMetastatic squamous cell carcinomaDefinitive malignant diagnosisMean patient ageSalivary glandsCommon malignant neoplasmFalse-negative diagnosesPatient ageSecondary malignanciesMetastatic carcinomaCell carcinomaPathology databaseMalignant neoplasmsFNAB diagnosisFNAB casesMalignant diagnosisMetastatic chordomaAncillary studiesNasopharyngeal carcinomaAspiration biopsyAncillary testsOlder men
2014
Expression of ERCC1, TYMS, RRM1, TUBB3, non-muscle myosin II, myoglobin and MyoD1 in lung adenocarcinoma pleural effusions predicts survival in patients receiving platinum-based chemotherapy
JIANG H, WANG H, WANG S, PEI Z, FU Z, FANG C, WANG J, LU Q, WANG E, LI J. Expression of ERCC1, TYMS, RRM1, TUBB3, non-muscle myosin II, myoglobin and MyoD1 in lung adenocarcinoma pleural effusions predicts survival in patients receiving platinum-based chemotherapy. Molecular Medicine Reports 2014, 11: 3523-3532. PMID: 25573098, DOI: 10.3892/mmr.2014.3141.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma of LungAdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsBiomarkers, TumorDNA-Binding ProteinsDrug Resistance, NeoplasmEndonucleasesFemaleGene ExpressionHumansImmunohistochemistryKaplan-Meier EstimateLung NeoplasmsMaleMiddle AgedMyoD ProteinMyoglobinMyosin Type IIPlatinumPleural Effusion, MalignantPrognosisRibonucleoside Diphosphate ReductaseThymidylate SynthaseTubulinTumor Suppressor ProteinsConceptsExcision repair cross-complementing gene 1Expression of ERCC1Platinum-based chemotherapyMetastatic lung adenocarcinomaLung adenocarcinomaPleural effusionLung Adenocarcinoma Pleural EffusionsPlatinum-based chemotherapy treatmentTumor cellsUntreated lung adenocarcinomasSurvival of patientsMalignant pleural effusionPleural fluid samplesExpression levelsProtein expression levelsWestern blot analysisClinical outcomesPatient survivalLung cancerChemotherapy treatmentLung carcinomaNon-muscle myosin IIPatientsAdenocarcinomaSurvival rateFine‐needle aspiration biopsy of secondary neoplasms of the thyroid gland: A multi‐institutional study of 62 cases
Pusztaszeri M, Wang H, Cibas ES, Powers CN, Bongiovanni M, Ali S, Khurana KK, Michaels PJ, Faquin WC. Fine‐needle aspiration biopsy of secondary neoplasms of the thyroid gland: A multi‐institutional study of 62 cases. Cancer Cytopathology 2014, 123: 19-29. PMID: 25369542, DOI: 10.1002/cncy.21494.Peer-Reviewed Original ResearchConceptsFine-needle aspiration biopsySquamous cell carcinomaThyroid fine-needle aspiration biopsySecondary neoplasmsAncillary studiesAspiration biopsyThyroid glandAccuracy of FNABMean patient ageMean tumor sizeUnknown primary siteUseful ancillary studiesMulti-institutional studyPatient ageInitial diagnosisTumor sizeCell carcinomaClinical historyPrimary tumorMedical recordsDiagnostic difficultiesMean intervalCystic carcinomaPrimary siteAdenocarcinoma