1998
Molecular characterization of rabbit CPP32 and its function in vascular smooth muscle cell apoptosis
Wang H, Keiser J. Molecular characterization of rabbit CPP32 and its function in vascular smooth muscle cell apoptosis. American Journal Of Physiology 1998, 274: h1132-h1140. PMID: 9575916, DOI: 10.1152/ajpheart.1998.274.4.h1132.Peer-Reviewed Original ResearchConceptsCPP32 mRNASmooth muscle cellsDEVD-CHOSNP treatmentSignal transduction eventsCell death detection enzyme-linked immunosorbentDegradation of PARPApoptotic cell deathRabbit smooth muscle cellsVascular smooth muscle cell apoptosisCultured arterial smooth muscle cellsCaspase membersSmooth muscle cell apoptosisDNA fragmentation analysisMuscle cell apoptosisSubstrate recognitionTransduction eventsCPP32 proteinArterial smooth muscle cellsCultured smooth muscle cellsVascular smooth muscle cellsProtease familyDegenerate primersApoptosis pathwayCentral playerExpression of Membrane-Type Matrix Metalloproteinase in Rabbit Neointimal Tissue and Its Correlation with Matrix-Metalloproteinase-2 Activation
Wang H, Keiser J. Expression of Membrane-Type Matrix Metalloproteinase in Rabbit Neointimal Tissue and Its Correlation with Matrix-Metalloproteinase-2 Activation. Journal Of Vascular Research 1998, 35: 45-54. PMID: 9482695, DOI: 10.1159/000025564.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsAortaBase SequenceBlotting, NorthernCells, CulturedDNA, ComplementaryEnzyme ActivationGelatinasesGene ExpressionHumansMaleMatrix Metalloproteinase 2Matrix Metalloproteinases, Membrane-AssociatedMetalloendopeptidasesMolecular Sequence DataMuscle, Smooth, VascularPolymerase Chain ReactionRabbitsRNA ProbesRNA, MessengerSequence HomologyConceptsBalloon catheter de-endothelializationMMP-2 activationArterial SMCsTemporal expression patternsMembrane-type matrix metalloproteinasesMembrane-type matrix metalloproteinaseNorthern blot analysisMatrix metalloproteinasesExtracellular matrix degradationRabbit cDNAMammalian cellsMT-MMP-1Matrix metalloproteinase-2 activationMT-MMP-1 expressionExpression patternsVascular neointimal formationSequence analysisMMP-2MMP cDNAPhenotypic alterationsCDNAPeak expressionRNA probesBlot analysisMatrix degradation
1996
Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in rabbit aortic neointima after selective de-endothelialization
Wang H, Moore S, Alavi M. Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in rabbit aortic neointima after selective de-endothelialization. Atherosclerosis 1996, 126: 95-104. PMID: 8879438, DOI: 10.1016/0021-9150(96)05898-4.Peer-Reviewed Original ResearchConceptsTIMP-1 geneRabbit formsApparent homologyExtracellular matrix metabolismExpression systemTIMP-1 expressionSoluble proteinNorthern blotSitu hybridization techniqueEscherichia coliProtein levelsMatrix metabolismGenesAortic neointimaNeointimal SMCsHybridization techniqueNucleic acidsWestern blotTIMP-1Tissue inhibitorExpressionBlotMetalloproteinase-1CDNAInhibitors