2021
Deuterium metabolic imaging – Back to the future
De Feyter HM, de Graaf RA. Deuterium metabolic imaging – Back to the future. Journal Of Magnetic Resonance 2021, 326: 106932. PMID: 33902815, PMCID: PMC8083995, DOI: 10.1016/j.jmr.2021.106932.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNMR visibility of deuterium‐labeled liver glycogen in vivo
De Feyter HM, Thomas MA, Behar KL, de Graaf R. NMR visibility of deuterium‐labeled liver glycogen in vivo. Magnetic Resonance In Medicine 2021, 86: 62-68. PMID: 33590529, PMCID: PMC8005460, DOI: 10.1002/mrm.28717.Peer-Reviewed Original ResearchAnimalsDeuteriumGlucoseLiverLiver GlycogenMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMice
2020
Characterization of Kinetic Isotope Effects and Label Loss in Deuterium-Based Isotopic Labeling Studies
de Graaf RA, Thomas MA, Behar KL, De Feyter HM. Characterization of Kinetic Isotope Effects and Label Loss in Deuterium-Based Isotopic Labeling Studies. ACS Chemical Neuroscience 2020, 12: 234-243. PMID: 33319987, PMCID: PMC9890388, DOI: 10.1021/acschemneuro.0c00711.Peer-Reviewed Original ResearchAnimalsCarbon IsotopesDeuteriumGlutamic AcidGlutamineIsotope LabelingKineticsMagnetic Resonance SpectroscopyRats
2019
In vivo 13C and 1H‐[13C] MRS studies of neuroenergetics and neurotransmitter cycling, applications to neurological and psychiatric disease and brain cancer
Rothman DL, de Graaf R, Hyder F, Mason GF, Behar KL, De Feyter HM. In vivo 13C and 1H‐[13C] MRS studies of neuroenergetics and neurotransmitter cycling, applications to neurological and psychiatric disease and brain cancer. NMR In Biomedicine 2019, 32: e4172. PMID: 31478594, DOI: 10.1002/nbm.4172.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAnimalsBrain NeoplasmsCarbon IsotopesHumansMagnetic Resonance SpectroscopyMental DisordersNeurotransmitter AgentsSynaptic Transmission
2017
Selective proton‐observed, carbon‐edited (selPOCE) MRS method for measurement of glutamate and glutamine 13C‐labeling in the human frontal cortex
De Feyter H, Herzog RI, Steensma BR, Klomp DWJ, Brown PB, Mason GF, Rothman DL, de Graaf R. Selective proton‐observed, carbon‐edited (selPOCE) MRS method for measurement of glutamate and glutamine 13C‐labeling in the human frontal cortex. Magnetic Resonance In Medicine 2017, 80: 11-20. PMID: 29134686, PMCID: PMC5876108, DOI: 10.1002/mrm.27003.Peer-Reviewed Original Research
2011
13C MRS studies of neuroenergetics and neurotransmitter cycling in humans
Rothman DL, De Feyter HM, de Graaf R, Mason GF, Behar KL. 13C MRS studies of neuroenergetics and neurotransmitter cycling in humans. NMR In Biomedicine 2011, 24: 943-957. PMID: 21882281, PMCID: PMC3651027, DOI: 10.1002/nbm.1772.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAgingAlzheimer DiseaseAnimalsBrainCarbon IsotopesCitric Acid CycleEnergy MetabolismGlutamic AcidGlutamineHumansMagnetic Resonance SpectroscopyNeuronsNeurotransmitter AgentsConceptsNeurotransmitter cyclingMRS studiesHigh neuronal activityHuman brain diseasesOnly noninvasive methodBrain metabolismGlutamate neurotransmissionNeuronal activityPsychiatric diseasesNeuronal functionBrain diseasesBrain functionClinical researchNeuroenergeticsNoninvasive methodMRSMRS measurementsHuman researchDiseaseBrain statesRecent findingsImportant new informationHumansMetabolic pathwaysNeurotransmission