2018
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair
Shook BA, Wasko RR, Rivera-Gonzalez GC, Salazar-Gatzimas E, López-Giráldez F, Dash BC, Muñoz-Rojas AR, Aultman KD, Zwick RK, Lei V, Arbiser JL, Miller-Jensen K, Clark DA, Hsia HC, Horsley V. Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair. Science 2018, 362 PMID: 30467144, PMCID: PMC6684198, DOI: 10.1126/science.aar2971.Peer-Reviewed Original ResearchConceptsDifferential gene expressionAdipocyte precursorsExtracellular matrix moleculesGene expressionTransplantation assaysMatrix moleculesFactor C.Factor 1Insulin-like growth factor-1Cell populationsTissue resilienceDistinct subpopulationsGrowth factor-1Profibrotic cellsTissue repairMultiple mouse modelsECM depositionSkin repairTissue dysfunctionProliferationMouse modelMyofibroblastsWoundingMacrophagesRepair
2004
Coregulation of Fibronectin Signaling and Matrix Contraction by Tenascin-C and Syndecan-4
Midwood KS, Valenick LV, Hsia HC, Schwarzbauer JE. Coregulation of Fibronectin Signaling and Matrix Contraction by Tenascin-C and Syndecan-4. Molecular Biology Of The Cell 2004, 15: 5670-5677. PMID: 15483051, PMCID: PMC532045, DOI: 10.1091/mbc.e04-08-0759.Peer-Reviewed Original ResearchConceptsSyndecan-4 functionsSyndecan-4Actin stress fiber formationFocal adhesion kinaseMatrix contractionStress fiber formationExtracellular matrix proteinsEfficient tissue repairEffects of tenascinProvisional matrixTissue repairHeparan sulfate proteoglycanAdhesion kinaseCell spreadingSignaling pathwaysMatrix proteinsFibronectin signalingThree-dimensional fibrinExtracellular matrixFiber formationSulfate proteoglycanCell interactionsFibroblast morphologyTenascinFibroblast response