2020
Induced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing
Gorecka J, Gao X, Fereydooni A, Dash BC, Luo J, Lee SR, Taniguchi R, Hsia HC, Qyang Y, Dardik A. Induced pluripotent stem cell-derived smooth muscle cells increase angiogenesis and accelerate diabetic wound healing. Regenerative Medicine 2020, 15: 1277-1293. PMID: 32228292, PMCID: PMC7304438, DOI: 10.2217/rme-2019-0086.Peer-Reviewed Original ResearchConceptsSmooth muscle cellsMuscle cellsDiabetic wound healingWound healingPro-angiogenic cytokinesMurine AdiposeStem cellsType macrophagesCollagen scaffoldsCultured mediumM2-type macrophagesCellsNumber of totalNew candidatesAngiogenesisNude miceDiabetic woundsPromising new candidateScaffoldsHealingCytokinesExpressionSecreteWoundsAdipose
2019
Evidence-Based Gardening: Using Palliative Approaches to Cure Complex Wounds.
Ching AH, Le N, Norwich-Cavanaugh A, Hsia HC. Evidence-Based Gardening: Using Palliative Approaches to Cure Complex Wounds. Annals Of Plastic Surgery 2019, 83: s45-s49. PMID: 31513065, DOI: 10.1097/sap.0000000000002100.Peer-Reviewed Original Research
2018
The Impact of Microbial Communities on Wound Healing
Xu Z, Hsia HC. The Impact of Microbial Communities on Wound Healing. Annals Of Plastic Surgery 2018, 81: 113-123. PMID: 29746280, DOI: 10.1097/sap.0000000000001450.Peer-Reviewed Original ResearchConceptsWound healingVenous insufficiency ulcersHealth care systemClinical factorsDefinitive treatmentDiabetic footPressure ulcersMicrobiome findingsAcute woundsImproved healingEnormous burdenChronic woundsComparison of findingsWound microbiotaBacteriophage therapyCare systemWound microbiomeExact roleWoundsHealingMore studiesUlcersMicrobiome compositionMajor bacteriaMicrobiome
2015
SDF‐1 liposomes promote sustained cell proliferation in mouse diabetic wounds
Olekson MA, Faulknor R, Bandekar A, Sempkowski M, Hsia HC, Berthiaume F. SDF‐1 liposomes promote sustained cell proliferation in mouse diabetic wounds. Wound Repair And Regeneration 2015, 23: 711-723. PMID: 26110250, DOI: 10.1111/wrr.12334.Peer-Reviewed Original ResearchConceptsStromal cell-derived factor-1Acellular dermisCell-derived factor-1Cell proliferationRestoration of skinChronic skin woundsImproved wound closurePersistent cell proliferationCommon complicationGranulation tissue thicknessIschemic tissueProper revascularizationDay 28Day 21Diabetic woundsSuch woundsWound closureSkin woundsDermisFactor 1Tissue thicknessWoundsProliferation