2020
Revisiting the Radiation Therapy Oncology Group 1221 Hypothesis: Treatment for Stage III/IV HPV-Negative Oropharyngeal Cancer
Jacobs D, Torabi SJ, Park HS, Rahmati R, Young MR, Mehra S, Judson BL. Revisiting the Radiation Therapy Oncology Group 1221 Hypothesis: Treatment for Stage III/IV HPV-Negative Oropharyngeal Cancer. Otolaryngology 2020, 164: 1240-1248. PMID: 33198564, DOI: 10.1177/0194599820969613.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseHPV-negative oropharyngeal cancersChemoradiation therapyOverall survivalCancer DatabaseOropharyngeal cancerHPV-negative oropharyngeal squamous cell carcinomaLarge national cancer databaseNeck cancer-specific survivalOropharyngeal squamous cell carcinomaCox proportional hazards regressionKaplan-Meier survival analysisCancer-specific survivalImproved overall survivalMultivariable Cox regressionRetrospective cohort studyAdjuvant chemoradiation therapyUse of surgeryEnd Results ProgramProportional hazards regressionSquamous cell carcinomaSEER cohortAdjuvant therapyCohort studySEER database
2017
Role of Adjuvant Treatment in Esophageal Cancer With Incidental Pathologic Node Positivity
Gao SJ, Park HS, Corso CD, Rutter CE, Kim AW, Johung KL. Role of Adjuvant Treatment in Esophageal Cancer With Incidental Pathologic Node Positivity. The Annals Of Thoracic Surgery 2017, 104: 267-274. PMID: 28456393, DOI: 10.1016/j.athoracsur.2017.01.092.Peer-Reviewed Original ResearchConceptsMargin-positive patientsSurgical resectionEsophageal cancer patientsMargin-negative patientsAdjuvant treatmentChemoradiation therapyOverall survivalCarcinoma patientsCancer patientsMultivariable Cox regression analysisNational Cancer Data BaseSquamous cell carcinoma patientsPathologic nodal involvementPathologic node positivityConcurrent chemoradiation therapyAdjuvant chemoradiation therapyCell carcinoma patientsEsophageal carcinoma patientsCox regression analysisFurther prospective studiesOptimal adjuvant treatmentLog-rank testKaplan-Meier estimationAdjuvant chemotherapyN0 patients