Quantifying Treatment Selection Bias Effects on Survival in National Database Studies: Findings from Low-Risk Prostate Cancer Patients
Miccio J, Talcott W, Jairam V, Park H, Yu J, Leapman M, King M, Nguyen P, Kann B. Quantifying Treatment Selection Bias Effects on Survival in National Database Studies: Findings from Low-Risk Prostate Cancer Patients. International Journal Of Radiation Oncology • Biology • Physics 2020, 108: e397. DOI: 10.1016/j.ijrobp.2020.07.2439.Peer-Reviewed Original ResearchLow-risk prostate cancer patientsNational database studyProstate cancer patientsCancer patientsDatabase studyPatientsQuantifying treatment selection bias effect on survival in comparative effectiveness research: findings from low-risk prostate cancer patients
Miccio JA, Talcott WJ, Jairam V, Park HS, Yu JB, Leapman MS, Johnson SB, King MT, Nguyen PL, Kann BH. Quantifying treatment selection bias effect on survival in comparative effectiveness research: findings from low-risk prostate cancer patients. Prostate Cancer And Prostatic Diseases 2020, 24: 414-422. PMID: 32989262, DOI: 10.1038/s41391-020-00291-3.Peer-Reviewed Original ResearchConceptsProstate cancer-specific survivalLow-risk prostate cancerExternal beam radiotherapyTreatment selection biasOverall survivalRadical prostatectomyProstate cancerOS differenceLow-risk prostate cancer patientsCancer-specific survivalEnd Results (SEER) databaseProstate cancer patientsClinical trial designEffectiveness researchComparative effectiveness researchPropensity-score matchingMethodsThe SurveillanceTreatment guidelinesResults databaseEntire cohortResultsA totalCancer patientsTreatment modalitiesNational registryPatient management