2020
Nationwide patterns of hemorrhagic stroke among patients hospitalized with brain metastases: influence of primary cancer diagnosis and anticoagulation
Lee V, Jairam V, Yu JB, Park HS. Nationwide patterns of hemorrhagic stroke among patients hospitalized with brain metastases: influence of primary cancer diagnosis and anticoagulation. Scientific Reports 2020, 10: 10084. PMID: 32572113, PMCID: PMC7308286, DOI: 10.1038/s41598-020-67316-8.Peer-Reviewed Original ResearchConceptsBrain metastasesLong-term anticoagulationIntracerebral hemorrhageKidney cancerHigh riskUtilization Project Nationwide Inpatient SampleDiagnosis of ICHHospital-related characteristicsRisks of anticoagulationPrimary cancer diagnosisMultivariable logistic regressionNationwide Inpatient SampleLonger lengthDiagnosis of melanomaMann-Whitney UHemorrhagic strokeNeurologic dysfunctionConcurrent diagnosisSignificant morbiditySecondary diagnosisInpatient SampleBaseline differencesDecreased qualityAnticoagulationHealthcare costs
2011
Delayed Radiation-Induced Vasculitic Leukoencephalopathy
Rauch PJ, Park HS, Knisely JP, Chiang VL, Vortmeyer AO. Delayed Radiation-Induced Vasculitic Leukoencephalopathy. International Journal Of Radiation Oncology • Biology • Physics 2011, 83: 369-375. PMID: 22024206, DOI: 10.1016/j.ijrobp.2011.06.1982.Peer-Reviewed Original ResearchConceptsGamma knife radiosurgeryKnife radiosurgeryRadiation therapyYale-New Haven HospitalRadiation-induced leukoencephalopathyHigh-dose radiation fieldT cell infiltrationMetastatic brain cancerFocused radiation therapyMedium-sized vesselsNew Haven HospitalActive vasculitisLeukoencephalopathic changesVasculitic componentBrain metastasesVascular sclerosisNeuropathologic examinationSignificant morbiditySurgical managementTumor recurrencePathological evidenceHistopathologic observationsLeukoencephalopathyPathological differencesBrain cancer