2019
Treatment-Related Complications of Systemic Therapy and Radiotherapy
Jairam V, Lee V, Park HS, Thomas CR, Melnick ER, Gross CP, Presley CJ, Adelson KB, Yu JB. Treatment-Related Complications of Systemic Therapy and Radiotherapy. JAMA Oncology 2019, 5: 1028-1035. PMID: 30946433, PMCID: PMC6583836, DOI: 10.1001/jamaoncol.2019.0086.Peer-Reviewed Original ResearchConceptsTreatment-related complicationsOverall ED visitsAcute kidney injuryED visitsSystemic therapyInpatient admissionsEmergency departmentKidney injuryCommon complicationMAIN OUTCOMEUtilization Project Nationwide Emergency Department SampleFinancial burdenNationwide Emergency Department SampleHospital-related factorsClinical Modification codesEmergency Department SampleClinical Classification SoftwareTotal financial burdenInternational Statistical ClassificationOverall financial burdenHigh rateRelated Health ProblemsAcute complicationsStudy cohortNinth Revision
2016
Postoperative Radiotherapy Patterns of Care and Survival Implications for Medulloblastoma in Young Children
Kann BH, Park HS, Lester-Coll NH, Yeboa DN, Benitez V, Khan AJ, Bindra RS, Marks AM, Roberts KB. Postoperative Radiotherapy Patterns of Care and Survival Implications for Medulloblastoma in Young Children. JAMA Oncology 2016, 2: 1574-1581. PMID: 27491009, DOI: 10.1001/jamaoncol.2016.2547.Peer-Reviewed Original ResearchConceptsPostoperative radiotherapyOverall survivalMultivariable logistic regressionNational Cancer Data BaseLogistic regressionAdjuvant chemotherapy strategyLow facility volumeNational treatment patternsMultivariable Cox regressionLong-term morbidityYear of diagnosisDay of surgeryKaplan-Meier analysisNational database analysisPoor overall survivalLog-rank testYoung childrenAge 3Adjuvant chemotherapyRadiotherapy patternsRadiotherapy utilizationWorse survivalDistant metastasisMultivariable analysisTreatment patterns
2014
Assessment of National Practice for Palliative Radiation Therapy for Bone Metastases Suggests Marked Underutilization of Single-Fraction Regimens in the United States
Rutter CE, Yu JB, Wilson LD, Park HS. Assessment of National Practice for Palliative Radiation Therapy for Bone Metastases Suggests Marked Underutilization of Single-Fraction Regimens in the United States. International Journal Of Radiation Oncology • Biology • Physics 2014, 91: 548-555. PMID: 25542310, DOI: 10.1016/j.ijrobp.2014.10.045.Peer-Reviewed Original ResearchConceptsNational Cancer Data BaseBone metastasesRadiation therapyMultiple fraction radiation therapyNon-private health insuranceSingle-fraction regimensPalliative radiation therapyProportion of patientsValue-based treatment decisionsRadiation therapy regimensMultiple-fraction treatmentsSingle-fraction treatmentCost-conscious careIndependent predictorsOsseous metastasesRandomized evidenceTherapy regimensLung cancerTreatment decisionsVertebral sitesClinical practicePatientsMarked underutilizationOlder ageSingle fraction
2009
Treatment patterns of aging Americans with differentiated thyroid cancer
Park HS, Roman SA, Sosa JA. Treatment patterns of aging Americans with differentiated thyroid cancer. Cancer 2009, 116: 20-30. PMID: 19908255, DOI: 10.1002/cncr.24717.Peer-Reviewed Original ResearchConceptsDifferentiated thyroid cancerElderly patientsTotal thyroidectomyRadioactive iodineYounger patientsThyroid cancerMultivariate analysisStage IV diseaseEnd Results (SEER) databaseCurrent practice guidelinesLong-term outcomesAge 65 yearsUse of thyroidectomyNonpapillary histologyRAI treatmentAdvanced diseaseWorse survivalImproved survivalPathologic characteristicsResults databaseTreatment patternsExtrathyroid extensionLarge tumorsPractice guidelinesPatients