2016
Platelet production and kinetics
Tormey C, Rinder H. Platelet production and kinetics. 2016, 206-214. DOI: 10.1002/9781119013020.ch17.ChaptersDemarcation membrane systemPro-platelet formationPlatelet productionGenetic controlComplex pathwaysMegakaryocyte proliferationRegulationCurrent understandingMembrane systemNew insightsPlatelet lifespanBone marrowProductionMegakaryocytesPathwayStructural regulationMaturationProliferationLifespanUnderstanding
2001
Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production
Perez L, Rinder H, Wang C, Tracey J, Maun N, Krause D. Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production. Blood 2001, 97: 1635-1643. PMID: 11238102, DOI: 10.1182/blood.v97.6.1635.Peer-Reviewed Original ResearchConceptsPeripheral blood stem cellsHuman peripheral blood stem cellsPlatelet productionVivo modelStudy of megakaryocytopoiesisCFU-MKHuman megakaryocytopoiesisImmunodeficient miceBone marrowHuman plateletsExogenous cytokinesNOD/SCID miceHuman hematopoiesisBlood stem cellsHuman cell engraftmentPlatelet developmentNonobese diabetic/Lymphoid lineageStem cellsHuman blood CD34MegakaryocytopoiesisPeripheral bloodCytokine stimulationMurine recipientsThrombin stimulation