1998
Platelet function testing by flow cytometry.
Rinder H. Platelet function testing by flow cytometry. Clinical Laboratory Science 1998, 11: 365-72. PMID: 10345505.Peer-Reviewed Original ResearchConceptsFlow cytometryPlatelet functionEx vivo platelet functionVivo platelet functionPlatelet function testingIntracellular calcium fluxExposure of plateletsPlatelet glycoprotein receptorsFluorescent monoclonal antibodiesFunction testingPlatelet aggregationActivation statusCalcium fluxMonoclonal antibodiesMicroparticle generationCytometryGranule contentsCytometric methodologyPlateletsGlycoprotein receptorsSecretionAntibodiesReceptors
1996
Characterization of the P-selectin ligand on human hematopoietic progenitors.
Tracey J, Rinder H. Characterization of the P-selectin ligand on human hematopoietic progenitors. Experimental Hematology 1996, 24: 1494-500. PMID: 8950232.Peer-Reviewed Original ResearchConceptsP-selectin glycoprotein ligand-1P-selectinMature neutrophilsPlatelet P-selectinTreatment of CD34Surface of CD34PSGL-1 expressionPreincubation of CD34Platelet adhesionTransplanted stem cellsP-selectin ligandsControl epitopesKG1a cell lineCD34MoAbMonoclonal antibodiesProgenitor cellsCD34 moleculeHuman hematopoietic progenitorsChelation of calciumPhorbol ester treatmentLigand 1Platelet bindingCell linesEpitopes
1994
Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*
Rinder H, Tracey J, Rinder C, Leitenberg D, Smith B. Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*. Thrombosis And Haemostasis 1994, 72: 750-756. PMID: 7534948, DOI: 10.1055/s-0038-1648953.Peer-Reviewed Original ResearchConceptsNeutrophil-platelet conjugatesP-selectinP-selectin-mediated platelet adhesionDREG-56Platelet activationL-selectinPlatelet P-selectin expressionP-selectin-expressing plateletsP-selectin-positive plateletsLeukocyte-platelet conjugatesNeutrophil-platelet adhesionPlatelet P-selectinP-selectin expressionWhole blood modelLeukocyte-platelet adhesionPlatelet adhesionNeutrophil activationLeukocyte activationNeutrophil adhesionBaseline levelsNeutrophilsUnstimulated leukocytesMonoclonal antibodiesEndothelial cellsImmediate rise
1991
Platelet Activation and Aggregation during Cardiopulmonary Bypass
Rinder C, Bohnert J, Rinder H, Mitchell J, Ault K, Hillman R. Platelet Activation and Aggregation during Cardiopulmonary Bypass. Anesthesiology 1991, 75: 388-393. PMID: 1716077, DOI: 10.1097/00000542-199109000-00002.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypassPlatelet activationPlatelet aggregationExtracorporeal circulationEarly postoperative periodAlpha-granule releaseGMP-140 expressionPlatelet factor 4Granule membrane protein-140Alpha-granule membrane proteinPlatelet surface membranePostoperative periodPlatelet dysfunctionPlasma concentrationsIndividual patientsBypassFlow cytometryPlatelet defectsGranule productsMonoclonal antibodiesProtein 140Factor 4PlateletsPatientsAggregation defect