2022
Platelet production and kinetics
Binns T, Tormey C, Rinder H. Platelet production and kinetics. 2022, 158-167. DOI: 10.1002/9781119719809.ch15.ChaptersComplex biological processesPlatelet productionEpigenetic effectorsRegulatory RNAsMegakaryocyte differentiationPlatelet biogenesisAnucleate cellsGenetic regulationMatrix metalloproteinase proteinsNormal platelet productionMammalian physiologyTranscription factorsProplatelet processesSinusoidal blood vesselsBiological processesMature megakaryocytesMegakaryopoiesisMetalloproteinase proteinsMegakaryocytesHuman physiologyNew insightsEndothelial cellsTurnover rateNormal hemostasisPhysiology
2016
Platelet production and kinetics
Tormey C, Rinder H. Platelet production and kinetics. 2016, 206-214. DOI: 10.1002/9781119013020.ch17.ChaptersDemarcation membrane systemPro-platelet formationPlatelet productionGenetic controlComplex pathwaysMegakaryocyte proliferationRegulationCurrent understandingMembrane systemNew insightsPlatelet lifespanBone marrowProductionMegakaryocytesPathwayStructural regulationMaturationProliferationLifespanUnderstanding
2001
Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production
Perez L, Rinder H, Wang C, Tracey J, Maun N, Krause D. Xenotransplantation of immunodeficient mice with mobilized human blood CD34+ cells provides an in vivo model for human megakaryocytopoiesis and platelet production. Blood 2001, 97: 1635-1643. PMID: 11238102, DOI: 10.1182/blood.v97.6.1635.Peer-Reviewed Original ResearchConceptsPeripheral blood stem cellsHuman peripheral blood stem cellsPlatelet productionVivo modelStudy of megakaryocytopoiesisCFU-MKHuman megakaryocytopoiesisImmunodeficient miceBone marrowHuman plateletsExogenous cytokinesNOD/SCID miceHuman hematopoiesisBlood stem cellsHuman cell engraftmentPlatelet developmentNonobese diabetic/Lymphoid lineageStem cellsHuman blood CD34MegakaryocytopoiesisPeripheral bloodCytokine stimulationMurine recipientsThrombin stimulation
1996
Reticulated platelet values in normal and thrombocytopenic neonates
Peterec S, Brennan S, Rinder H, Wnek J, Beardsley D. Reticulated platelet values in normal and thrombocytopenic neonates. The Journal Of Pediatrics 1996, 129: 269-274. PMID: 8765626, DOI: 10.1016/s0022-3476(96)70253-6.Peer-Reviewed Original ResearchConceptsWeeks of gestationRP percentagePlatelet destructionPercentage of RPImmune thrombocytopeniaTerm neonatesImmune platelet destructionGestational age groupsPlatelet productionRP countsPreterm neonatesThrombocytopenic neonatesNeonatal thrombocytopeniaOld neonatePlatelet valuesThrombocytopeniaNeonatesHealthy adultsAge groupsRibonucleic acid contentWeeksPreliminary dataGestationBirthAdults
1994
Noninvasive measurement of platelet kinetics in normal and hypertensive pregnancies
Rinder H, Bonan J, Anandan S, Rinder C, Rodrigues P, Smith B. Noninvasive measurement of platelet kinetics in normal and hypertensive pregnancies. American Journal Of Obstetrics And Gynecology 1994, 170: 117-122. DOI: 10.1016/s0002-9378(13)70291-6.Peer-Reviewed Original ResearchPregnancy-induced hypertensionNormal pregnancyPlatelet countPlatelet kineticsImmune platelet destructionSerum antiplatelet antibodiesPlatelet-associated immunoglobulinsLarge prospective studiesNormal nonpregnant womenOnset of symptomsPlatelet productionHypertensive pregnanciesAntiplatelet antibodiesNonpregnant womenClinical courseNulliparous womenWeeks' gestationPlatelet destructionProspective studyPregnant womenClinical signsPlatelet valuesSerial measurementsBlood samplesPlatelet decrease