1994
Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*
Rinder H, Tracey J, Rinder C, Leitenberg D, Smith B. Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*. Thrombosis And Haemostasis 1994, 72: 750-756. PMID: 7534948, DOI: 10.1055/s-0038-1648953.Peer-Reviewed Original ResearchMeSH KeywordsCell Adhesion MoleculesHumansMonocytesNeutrophil ActivationP-SelectinPlatelet AdhesivenessPlatelet Membrane GlycoproteinsConceptsNeutrophil-platelet conjugatesP-selectinP-selectin-mediated platelet adhesionDREG-56Platelet activationL-selectinPlatelet P-selectin expressionP-selectin-expressing plateletsP-selectin-positive plateletsLeukocyte-platelet conjugatesNeutrophil-platelet adhesionPlatelet P-selectinP-selectin expressionWhole blood modelLeukocyte-platelet adhesionPlatelet adhesionNeutrophil activationLeukocyte activationNeutrophil adhesionBaseline levelsNeutrophilsUnstimulated leukocytesMonoclonal antibodiesEndothelial cellsImmediate rise
1993
Aspirin Does Not Inhibit Adenosine Diphosphate-Induced Platelet α-Granule Release
Rinder C, Student L, Bonan J, Rinder H, Smith B. Aspirin Does Not Inhibit Adenosine Diphosphate-Induced Platelet α-Granule Release. Blood 1993, 82: 505-512. PMID: 7687162, DOI: 10.1182/blood.v82.2.505.505.Peer-Reviewed Original ResearchConceptsP-selectin expressionAlpha-granule secretionPlatelet alpha-granule secretionAspirin treatmentP-selectinGranule secretionPlatelet alpha-granule releaseArachidonic acidCyclooxygenase-dependent metabolitesPlatelet surface expressionPlatelet α-granule releasePlatelet dense granule secretionAlpha-granule releaseΑ-granule releaseDense granule secretionPolymorphonuclear lymphocytesAmiloride treatmentLipoxygenase inhibitorsAspirinSecretionWhole bloodPlatelet-platelet interactionsTreatmentInvolvement of metabolitesPlatelets
1992
Cardiopulmonary Bypass Induces Leukocyte-Platelet Adhesion
Rinder C, Bonan J, Rinder H, Mathew J, Hines R, Smith B. Cardiopulmonary Bypass Induces Leukocyte-Platelet Adhesion. Blood 1992, 79: 1201-1205. PMID: 1371416, DOI: 10.1182/blood.v79.5.1201.1201.Peer-Reviewed Original ResearchMeSH KeywordsBlood PlateletsCardiopulmonary BypassCell AdhesionHumansKineticsLeukocytesMacrophage-1 AntigenMonocytesNeutrophilsPlatelet ActivationPlatelet Membrane GlycoproteinsP-SelectinConceptsLeukocyte-platelet conjugatesCardiopulmonary bypassMonocyte-platelet conjugatesEnd of CPBStart of CPBActivation of monocytesAlpha-granule releaseGMP-140 expressionGranule membrane protein-140Time courseLeukocyte-platelet adhesionCD11b expressionMonocyte activationSurface CD11bWhole bloodGMP-140Surface expressionProtein 140Increased numberCD11bBypassMonocytesPlateletsPlatelet adhesionConjugatesActivation of platelet concentrate during preparation and storage.
Rinder H, Snyder E. Activation of platelet concentrate during preparation and storage. Blood Cells Molecules And Diseases 1992, 18: 445-56; discussion 457-60. PMID: 1283703.Peer-Reviewed Original Research
1991
Dynamics of leukocyte-platelet adhesion in whole blood.
Rinder H, Bonan J, Rinder C, Ault K, Smith B. Dynamics of leukocyte-platelet adhesion in whole blood. Blood 1991, 78: 1730-7. PMID: 1717069, DOI: 10.1182/blood.v78.7.1730.bloodjournal7871730.Peer-Reviewed Original ResearchActivated and unactivated platelet adhesion to monocytes and neutrophils.
Rinder H, Bonan J, Rinder C, Ault K, Smith B. Activated and unactivated platelet adhesion to monocytes and neutrophils. Blood 1991, 78: 1760-9. PMID: 1717070, DOI: 10.1182/blood.v78.7.1760.bloodjournal7871760.Peer-Reviewed Original ResearchModulation of Platelet Surface Adhesion Receptors during Cardiopulmonary Bypass
Rinder C, Mathew J, Rinder H, Bonan J, Ault K, Smith B. Modulation of Platelet Surface Adhesion Receptors during Cardiopulmonary Bypass. Anesthesiology 1991, 75: 563-570. PMID: 1718190, DOI: 10.1097/00000542-199110000-00004.Peer-Reviewed Original ResearchMeSH KeywordsCardiopulmonary BypassCD36 AntigensFlow CytometryHumansPlatelet ActivationPlatelet AdhesivenessPlatelet Membrane GlycoproteinsP-SelectinReceptors, Cell SurfaceReceptors, CytoadhesinConceptsIIb/IIIaCardiopulmonary bypassGlycoprotein IIb/IIIaPlatelet activationQualitative platelet defectsGlycoprotein IVGlycoprotein IbAlpha-granule releaseGranule membrane protein-140Surface glycoprotein IbHLA APlatelet functionBaseline valuesVon Willebrand factor receptorBypassThrombospondin receptorGlycoprotein Ib expressionFlow cytometryIb expressionPlatelet defectsSelective decreasePlatelet receptorsFactor receptorReceptorsProtein 140Platelet Activation and Aggregation during Cardiopulmonary Bypass
Rinder C, Bohnert J, Rinder H, Mitchell J, Ault K, Hillman R. Platelet Activation and Aggregation during Cardiopulmonary Bypass. Anesthesiology 1991, 75: 388-393. PMID: 1716077, DOI: 10.1097/00000542-199109000-00002.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypassPlatelet activationPlatelet aggregationExtracorporeal circulationEarly postoperative periodAlpha-granule releaseGMP-140 expressionPlatelet factor 4Granule membrane protein-140Alpha-granule membrane proteinPlatelet surface membranePostoperative periodPlatelet dysfunctionPlasma concentrationsIndividual patientsBypassFlow cytometryPlatelet defectsGranule productsMonoclonal antibodiesProtein 140Factor 4PlateletsPatientsAggregation defectProgressive platelet activation with storage: evidence for shortened survival of activated platelets after transfusion
Rinder H, Murphy M, Mitchell J, Stocks J, Ault K, Hillman R. Progressive platelet activation with storage: evidence for shortened survival of activated platelets after transfusion. Transfusion 1991, 31: 409-414. PMID: 1710840, DOI: 10.1046/j.1537-2995.1991.31591263195.x.Peer-Reviewed Original ResearchConceptsPercentage of plateletsPlatelet activationNormal subjectsProgressive platelet activationThrombocytopenic cancer patientsPlatelet concentrate transfusionAlpha-granule membrane protein-140Significant platelet activationConcentrate transfusionPlatelet incrementCancer patientsPlatelet recoveryThrombocytopenic patientsAutologous plateletsPosttransfusion recoveryFlow cytometryStandard blood bank conditionsGMP-140Protein 140PlateletsTransfusionPlatelet surfacePatientsSuch activationDay of collection
1989
Correlated measurement of platelet release and aggregation in whole blood
Ault K, Rinder H, Mitchell J, Rinder C, Lambrew C, Hillman R. Correlated measurement of platelet release and aggregation in whole blood. Cytometry 1989, 10: 448-455. PMID: 2475308, DOI: 10.1002/cyto.990100413.Peer-Reviewed Original ResearchAntibodies, MonoclonalBlood PlateletsFlow CytometryHumansPlatelet AggregationPlatelet Function TestsPlatelet Membrane GlycoproteinsP-Selectin