1997
Lymphocyte and monocyte subset changes during cardiopulmonary bypass: Effects of aging and gender
Rinder C, Mathew J, Rinder H, Tracey J, Davis E, Smith B. Lymphocyte and monocyte subset changes during cardiopulmonary bypass: Effects of aging and gender. Translational Research 1997, 129: 592-602. PMID: 9178725, DOI: 10.1016/s0022-2143(97)90193-1.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypassOlder patientsT cellsLower lymphocyte numbersPercentage of CD8Total lymphocyte countCardiac surgery patientsPostoperative day 1Age of patientsMononuclear cell subsetsNatural killer cellsExpression of CD11bPatterns of lymphocytesYears of ageEvidence of activationHLADR expressionInfectious complicationsLymphocyte subsetsElderly patientsLymphocyte countSurgery patientsYounger patientsCardiac surgeryLymphocyte numbersKiller cells
1991
Platelet Activation and Aggregation during Cardiopulmonary Bypass
Rinder C, Bohnert J, Rinder H, Mitchell J, Ault K, Hillman R. Platelet Activation and Aggregation during Cardiopulmonary Bypass. Anesthesiology 1991, 75: 388-393. PMID: 1716077, DOI: 10.1097/00000542-199109000-00002.Peer-Reviewed Original ResearchConceptsCardiopulmonary bypassPlatelet activationPlatelet aggregationExtracorporeal circulationEarly postoperative periodAlpha-granule releaseGMP-140 expressionPlatelet factor 4Granule membrane protein-140Alpha-granule membrane proteinPlatelet surface membranePostoperative periodPlatelet dysfunctionPlasma concentrationsIndividual patientsBypassFlow cytometryPlatelet defectsGranule productsMonoclonal antibodiesProtein 140Factor 4PlateletsPatientsAggregation defectProgressive platelet activation with storage: evidence for shortened survival of activated platelets after transfusion
Rinder H, Murphy M, Mitchell J, Stocks J, Ault K, Hillman R. Progressive platelet activation with storage: evidence for shortened survival of activated platelets after transfusion. Transfusion 1991, 31: 409-414. PMID: 1710840, DOI: 10.1046/j.1537-2995.1991.31591263195.x.Peer-Reviewed Original ResearchConceptsPercentage of plateletsPlatelet activationNormal subjectsProgressive platelet activationThrombocytopenic cancer patientsPlatelet concentrate transfusionAlpha-granule membrane protein-140Significant platelet activationConcentrate transfusionPlatelet incrementCancer patientsPlatelet recoveryThrombocytopenic patientsAutologous plateletsPosttransfusion recoveryFlow cytometryStandard blood bank conditionsGMP-140Protein 140PlateletsTransfusionPlatelet surfacePatientsSuch activationDay of collection